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RESEARCH PAPER · Materials Science and Engineering C · 2015

Delivery system for mefenamic acid based on the nanocarrier layered double hydroxide: Physicochemical characterization and evaluation of anti-inflammatory and antinociceptive potential

Vanessa R. R. Cunha, Viviane Aparecida Guilherme, Eneida de Paula, Daniele Ribeiro de Araújo, Renan Oliveira Silva, Jand Venes Rolim Medeiros, José Roberto S. A. Leite, Philippe Alexandre Divina Petersen, Marianna Földvári, Helena Maria Petrilli, Vera Regina Leopoldo Constantino

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Delivery system for mefenamic acid based on the nanocarrier layered double hydroxide: Physicochemical characterization and evaluation of anti-inflammatory and antinociceptive potentialOriginalInorganic layered double hydroxides as a 4-hexyl resorcinol delivery system for topical applications10Layered double hydroxide and sulindac coiled and scrolled nanoassemblies for storage and drug release59Flexible polyurethane foam nanocomposites with modified layered double hydroxides60Preparation and optimization of a drug delivery system based on berberine chloride-immobilized MgAl hydrotalcite37Accessing the biocompatibility of layered double hydroxide by intramuscular implantation: histological and microcirculation evaluation100Modified drug release system based on Sulindac and layered double hydroxide: An in vivo Raman investigation20Delivery system for berberine chloride based on the nanocarrier ZnAl-layered double hydroxide: Physicochemical characterization, release behavior and evaluation of anti-bacterial potential52Clay–Polymer Nanocomposites for Controlled Drug Release12LAPONITE®-pilocarpine hybrid material: experimental and theoretical evaluation of pilocarpine conformation33Evaluation of anti-inflammatory potential of aqueous extract and polysaccharide fraction of Thuja occidentalis Linn. in mice38Controlled release of ibuprofen using Mg Al LDH nano carrier21Mg–Al and Zn–Al Layered Double Hydroxides Promote Dynamic Expression of Marker Genes in Osteogenic Differentiation by Modulating Mitogen‐Activated Protein Kinases71Combined solid-state NMR, FT-IR and computational studies on layered and porous materials184Functional intercalated nanocomposites with chitosan-glutathione-glycylsarcosine and layered double hydroxides for topical ocular drug delivery45Dual role of layered double hydroxide nanocomposites on antibacterial activity and degradation of tetracycline and oxytetracyline35L'élaboration des nouveaux (Bio)-matériaux et leurs applications dans le domaine médical0Mefenamic Acid-Layered Zinc Hydroxide Nanohybrids: A New Platform to Elaborate Drug Delivery Systems15Synthesis and characterization of ZnAl-NO3(-CO3) layered double hydroxide: A novel structure for intercalation and release of simvastatin110Iron-Based Layered Double Hydroxide Implants: Potential Drug Delivery Carriers with Tissue Biointegration Promotion and Blood Microcirculation Preservation48Hybrid NiAl layered double hydroxide: Characterization and in situ synchrotron XRD and vibrational spectroscopic studies under high-pressure9Nanomedicine for the effective and safe delivery of non-steroidal anti-inflammatory drugs: A review of preclinical research46Surface modification of fluorescent Tb3+-doped layered double hydroxides with hyperbranched polymers through host-guest interaction9Hidróxidos duplos lamelares: estudos da intercalação e liberação de N-acetil-L-cisteína0Adsolubilisation of thiacloprid pesticide into the layered zinc hydroxide salt intercalated with dodecyl sulphate, for controlled release formulation6Preparation of the Hybrids of Hydrotalcites and Chitosan by Urea Method and Their Antimicrobial Activities12Optimization of ZnAl/Chitosan Supra-Nano Hybrid Preparation as Efficient Antibacterial Material16Covalent polybenzimidazole-based triazine frameworks: A robust carrier for non-steroidal anti-inflammatory drugs34Correction: Sustainable waste management and recycling of Zn–Al layered double hydroxide after adsorption of levofloxacin as a safe anti-inflammatory nanomaterial10Fabrication of bionanocomposite based on LDH using biopolymer of gum arabic and chitosan-coating for sustained drug-release29Phytochemical species intercalated into layered double hydroxides: structural investigation and biocompatibility assays13Sustainable waste management and recycling of Zn–Al layered double hydroxide after adsorption of levofloxacin as a safe anti-inflammatory nanomaterial60Structural arrangement and properties of layered double hydroxide drug nanocarrier intercalated by sulindac and mefenamic acid solved by molecular simulation methods24Design of 3D multi-layered electrospun membranes embedding iron-based layered double hydroxide for drug storage and control of sustained release29Untitled work0New nanocarried phenobarbital formulation: Maintains better control of pentylenetetrazole-Induced seizures5Layered Double Hydroxides as Promising Excipients for Drug Delivery Purposes49Investigation about iron(III) incorporation into layered double hydroxides: Compositional and structural properties of Mg2FeyAl(1−y)(OH)6-Cl and Zn2FeyAl(1−y)(OH)6-Cl13Material híbrido orgânico-inorgânico de apocarotenoide natural e hidróxido duplo lamelar como emulsificante de pickering0Improved biological performance of ketoprofen using novel modified halloysite clay nanotubes21Innovative membrane containing iron-based layered double hydroxide intercalated with phyto therapeutic diterpenoid4Fe(III)‐Based Layered Double Hydroxides Carrying Model Naproxenate Anions: Compositional and Structural Aspects4Anti-Inflammatory and Analgesic Evaluation of a Phytochemical Intercalated into Layered Double Hydroxide13Limiting content of trivalent iron to form organic-inorganic single-phase layered double hydroxides hybrids by coprecipitation7Development of Dipeptide N–acetyl–L–cysteine Loaded Nanostructured Carriers Based on Inorganic Layered Hydroxides4Estudo de processo inflamatório articular por espectroscopia Raman: ação de compostos lamelares e detecção de alterações fisiológicas0Effect of Zn2Cr layered double hydroxide on photocatalytic hydroxylation of terephthalic acid and photodegradation of sodium diclofenac14Layered Double Hydroxide Nanocarriers: Potential Delivery Systems for Mefenamic Acid1κ-Carrageenan/sericin polymer matrix modified with different crosslinking agents and thermal crosslinking: Improved release profile of mefenamic acid9Recent Insights and Clinical Status on Novel Mefenamic Acid Nanocarriers for the Treatment of Rheumatoid Arthritis3Free-Standing Bacterial Films Reinforced with 2D Layered Double Hydroxide Nanosheets: A Step Towards Living Materials0Potential role of NSAIDs loaded nano-formulations to treat inflammatory diseases8Nanohybrid delivery systems for release of an anti-inflammatory drug based on the magnetic nanocomposites of Mg/Zn-Al layered double hydroxides6Free-standing bacterial films reinforced with 2D layered double hydroxide nanosheets: A biohybrid platform toward engineered living materials3Micro- and nanoencapsulation strategies for mefenamic acid delivery: carrier design, release mechanisms, and preclinical performance1Comparative study of ibuprofen intercalation into the interlayer space of Mg–Al layered double hydroxide (LDH) via two synthesis methods and release kinetics0

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  1. Inorganic layered double hydroxides as a 4-hexyl resorcinol delivery system for topical applications

    RSC Advances · 2016-01-01

    Damodar Mosangi, Sreejarani Kesavan Pillai, Lumbidzani Moyo, Suprakas Sinha Ray

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  2. Layered double hydroxide and sulindac coiled and scrolled nanoassemblies for storage and drug release

    RSC Advances · 2016-01-01

    Michele Aparecida Rocha, Philippe Alexandre Divina Petersen, Érico Teixeira‐Neto, Helena Maria Petrilli, Fabrice Leroux, Christine Taviot‐Guého, Vera Regina Leopoldo Constantino

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  3. Flexible polyurethane foam nanocomposites with modified layered double hydroxides

    Applied Clay Science · 2016-02-04

    Sandra Gómez-Fernández, Lorena Ugarte, Cristina Peña-Rodríguez, Manuela Zubitur, María Ángeles Corcuera, Arantxa Eceiza

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  4. Preparation and optimization of a drug delivery system based on berberine chloride-immobilized MgAl hydrotalcite

    International Journal of Pharmaceutics · 2016-05-01

    Mohamed Amine Djebbi, Zaineb Bouaziz, Alae Elabed, Moulay Sadiki, Soumya Elabed, Philippe Namour, Nicole J. Jaffrezic-Renault, Abdesslem Ben Haj Amara

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  5. Accessing the biocompatibility of layered double hydroxide by intramuscular implantation: histological and microcirculation evaluation

    Scientific Reports · 2016-08-02

    Vanessa R. R. Cunha, Rodrigo Barbosa de Souza, Ana Maria Cristina Rebello Pinto da Fonseca Martins, Ivan Hong Jun Koh, Vera Regina Leopoldo Constantino

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  6. Modified drug release system based on Sulindac and layered double hydroxide: An in vivo Raman investigation

    Vibrational Spectroscopy · 2016-09-15

    Otávio M. Gil, Michele Aparecida Rocha, Vera Regina Leopoldo Constantino, Ivan Hong Jun Koh, Dalva Lúcia Araújo de Faria

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  7. Delivery system for berberine chloride based on the nanocarrier ZnAl-layered double hydroxide: Physicochemical characterization, release behavior and evaluation of anti-bacterial potential

    International Journal of Pharmaceutics · 2016-10-19

    Mohamed Amine Djebbi, Alae Elabed, Zaineb Bouaziz, Moulay Sadiki, Soumya Elabed, Philippe Namour, Nicole J. Jaffrezic-Renault, Abdesslem Ben Haj Amara

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  8. Clay–Polymer Nanocomposites for Controlled Drug Release

    Elsevier eBooks · 2017-01-01

    Sorina Alexandra Gȃrea, Anda I. Voicu, Horia Iovu

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  9. LAPONITE®-pilocarpine hybrid material: experimental and theoretical evaluation of pilocarpine conformation

    RSC Advances · 2017-01-01

    Vanessa R. R. Cunha, Filipe C. D. A. Lima, Vanessa Y. Sakai, Leiz Maria Costa Véras, José Roberto S. A. Leite, Helena Maria Petrilli, Vera Regina Leopoldo Constantino

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  10. Evaluation of anti-inflammatory potential of aqueous extract and polysaccharide fraction of Thuja occidentalis Linn. in mice

    International Journal of Biological Macromolecules · 2017-07-24

    Irismara S. Silva, Lucas Antônio Duarte Nicolau, Francisca Beatriz M. Sousa, Simone de Araújo, Ana Patrícia de Oliveira, Thiago S.L. Araújo, Luan Kelves Miranda de Souza, Conceição S. Martins, Pedro Éverson Alexandre de Aquino, Lucas L. Carvalho, Renan Oliveira Silva, Pedró José Rolim Neto, Jand Venes Rolim Medeiros

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  11. Controlled release of ibuprofen using Mg Al LDH nano carrier

    IOP Conference Series Materials Science and Engineering · 2017-08-01

    Sudip Dasgupta

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  12. Mg–Al and Zn–Al Layered Double Hydroxides Promote Dynamic Expression of Marker Genes in Osteogenic Differentiation by Modulating Mitogen‐Activated Protein Kinases

    Advanced Healthcare Materials · 2017-12-27

    Ha Ram Kang, Célio Júnior da Costa Fernandes, Rodrigo A. da Silva, Vera Regina Leopoldo Constantino, Ivan Hong Jun Koh, Willian Fernando Zambuzzi

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  13. Combined solid-state NMR, FT-IR and computational studies on layered and porous materials

    Chemical Society Reviews · 2018-01-01

    Geo Paul, Chiara Bisio, Ilaria Braschi, Maurizio Cossi, Giorgio Gatti, Enrica Gianotti, Leonardo Marchese

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  14. Functional intercalated nanocomposites with chitosan-glutathione-glycylsarcosine and layered double hydroxides for topical ocular drug delivery

    International Journal of Nanomedicine · 2018-02-01

    Tingting Xu, Xiaoyue Xu, Yan Gu, Lei Fang, Feng Cao

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  15. Dual role of layered double hydroxide nanocomposites on antibacterial activity and degradation of tetracycline and oxytetracyline

    Chemosphere · 2018-05-02

    Zaineb Bouaziz, Laurence Soussan, Jean‐Marc Janot, Maguy Jaber, Abdesslem Ben Haj Amara, Sébastien Balme

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  16. L'élaboration des nouveaux (Bio)-matériaux et leurs applications dans le domaine médical

    Unknown journal · 2018-07-17

    Zaineb Bouaziz

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  17. Mefenamic Acid-Layered Zinc Hydroxide Nanohybrids: A New Platform to Elaborate Drug Delivery Systems

    Journal of Inorganic and Organometallic Polymers and Materials · 2018-10-16

    Hafezeh Nabipour, Seyed Hassan Jafari, Ehsan Naderikalali, Masoud Mozafari

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  18. Synthesis and characterization of ZnAl-NO3(-CO3) layered double hydroxide: A novel structure for intercalation and release of simvastatin

    Applied Surface Science · 2018-10-28

    Mana Yasaei, Mehrdad Khakbiz, Ebrahim Ghasemi, Ali Zamanian

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  19. Iron-Based Layered Double Hydroxide Implants: Potential Drug Delivery Carriers with Tissue Biointegration Promotion and Blood Microcirculation Preservation

    ACS Omega · 2018-12-26

    Mariana Pires Figueiredo, Vanessa R. R. Cunha, Fabrice Leroux, Christine Taviot‐Guého, MN Nakamae, Yongjian Kang, Rodrigo Barbosa de Souza, Ana M. Cristina R.P.F. Martins, Ivan Hong Jun Koh, Vera Regina Leopoldo Constantino

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  20. Hybrid NiAl layered double hydroxide: Characterization and in situ synchrotron XRD and vibrational spectroscopic studies under high-pressure

    Applied Clay Science · 2019-04-08

    Caroline Silva de Matos, Marcelo M. Nóbrega, Márcia L. A. Temperini, Vera Regina Leopoldo Constantino

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  21. Nanomedicine for the effective and safe delivery of non-steroidal anti-inflammatory drugs: A review of preclinical research

    European Journal of Pharmaceutics and Biopharmaceutics · 2019-06-21

    Hanan Al-Lawati, Ziyad Binkhathlan, Afsaneh Lavasanifar

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  22. Surface modification of fluorescent Tb3+-doped layered double hydroxides with hyperbranched polymers through host-guest interaction

    Materials Science and Engineering C · 2019-07-16

    Fengjie Deng, Huajian Zhou, Junyu Chen, Hongye Huang, Jianwen Tian, Qiang Huang, Yuanqing Wen, Meiying Liu, Xiaoyong Zhang, Yen Wei

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  23. Hidróxidos duplos lamelares: estudos da intercalação e liberação de N-acetil-L-cisteína

    Unknown journal · 2019-07-19

    Denise Eulálio

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  24. Adsolubilisation of thiacloprid pesticide into the layered zinc hydroxide salt intercalated with dodecyl sulphate, for controlled release formulation

    Materials Research Innovations · 2019-08-21

    Zuhailimuna Muda, Norhayati Hashim, Illyas Md Isa, Suzaliza Mustafar, Suriani Abu Bakar, Mazidah Mamat, Mohd Zobir Hussein

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  25. Preparation of the Hybrids of Hydrotalcites and Chitosan by Urea Method and Their Antimicrobial Activities

    Polymers · 2019-09-28

    Bi Foua Claude Alain Gohi, Hong‐Yan Zeng, Xiao‐Ju Cao, Kai‐Min Zou, Wenlin Shuai, Yi Diao

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  26. Optimization of ZnAl/Chitosan Supra-Nano Hybrid Preparation as Efficient Antibacterial Material

    International Journal of Molecular Sciences · 2019-11-14

    Bi Foua Claude Alain Gohi, Hong‐Yan Zeng, Sheng Xu, Kai‐Min Zou, Binyao Liu, Xiu Li Huang, Xiao-Ju Cao

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  27. Covalent polybenzimidazole-based triazine frameworks: A robust carrier for non-steroidal anti-inflammatory drugs

    Materials Science and Engineering C · 2019-11-21

    Mohammad Dinari, Nazanin Mokhtari, Somayeh Taymouri, Mohammad Reza Arshadi, Alireza Abbaspourrad

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  28. Correction: Sustainable waste management and recycling of Zn–Al layered double hydroxide after adsorption of levofloxacin as a safe anti-inflammatory nanomaterial

    RSC Advances · 2020-01-01

    Samar M. Mahgoub, Mohamed Refaat Shehata, Fatma I. Abo El‐Ela, Ahmed A. Farghali, Amal Zaher, Rehab Mahmoud

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  29. Fabrication of bionanocomposite based on LDH using biopolymer of gum arabic and chitosan-coating for sustained drug-release

    Journal of the Serbian Chemical Society · 2020-01-01

    Milad Abniki, Ali Moghimi, Fariborz Azizinejad

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  30. Phytochemical species intercalated into layered double hydroxides: structural investigation and biocompatibility assays

    New Journal of Chemistry · 2020-01-01

    Vanessa R. R. Cunha, Philippe Alexandre Divina Petersen, Rodrigo Barbosa de Souza, Ana M. Cristina R.P.F. Martins, Fabrice Leroux, Christine Taviot‐Guého, Helena Maria Petrilli, Ivan Hong Jun Koh, Vera Regina Leopoldo Constantino

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  31. Sustainable waste management and recycling of Zn–Al layered double hydroxide after adsorption of levofloxacin as a safe anti-inflammatory nanomaterial

    RSC Advances · 2020-01-01

    Samar M. Mahgoub, Mohamed Refaat Shehata, Fatma I. Abo El‐Ela, Ahmed A. Farghali, Amal Zaher, Rehab Mahmoud

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  32. Structural arrangement and properties of layered double hydroxide drug nanocarrier intercalated by sulindac and mefenamic acid solved by molecular simulation methods

    Applied Clay Science · 2020-03-26

    Milan Pšenička, Jakub Škoda, Miroslav Pospı́šil

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  33. Design of 3D multi-layered electrospun membranes embedding iron-based layered double hydroxide for drug storage and control of sustained release

    European Polymer Journal · 2020-04-08

    Mariana Pires Figueiredo, Géraldine Layrac, Anne Hébraud, Lionel Limousy, Jocelyne Brendlé, Guy Schlatter, Vera Regina Leopoldo Constantino

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  34. Untitled work

    International Journal of Pharmaceutical Sciences and Research · 2020-08-01

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  35. New nanocarried phenobarbital formulation: Maintains better control of pentylenetetrazole-Induced seizures

    Biotechnology Reports · 2020-10-09

    Lorena Cristina Nunes de Almeida, Beatriz de Andrade Marques, Rafaela Laranjeira Silva, Akira Otake Hamoy, Vanessa Jóia de Mello, Rosivaldo S. Borges, Frank Sales Nunes Brito, E. Longo, Marcos Anicete-Santos, Moisés Hamoy

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  36. Layered Double Hydroxides as Promising Excipients for Drug Delivery Purposes

    European Journal of Pharmaceutical Sciences · 2021-07-01

    André Luiz Moreira Domingues de Sousa, Widson Michael dos Santos, Myla Lôbo de Souza, Laysa Creusa Paes Barreto Barros Silva, Adriana Eun He Koo Yun, Cindy Siqueira Britto Aguilera, Beatriz de França Chagas, Larissa Araújo Rolim, Rosali Maria Ferreira da Silva, Pedró José Rolim Neto

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  37. Investigation about iron(III) incorporation into layered double hydroxides: Compositional and structural properties of Mg2FeyAl(1−y)(OH)6-Cl and Zn2FeyAl(1−y)(OH)6-Cl

    Journal of Alloys and Compounds · 2021-07-16

    Mariana Pires Figueiredo, Alfredo Duarte, Victor Vendruscolo, Rodolphe Thirouard, Vera Regina Leopoldo Constantino, Christine Taviot‐Guého

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  38. Material híbrido orgânico-inorgânico de apocarotenoide natural e hidróxido duplo lamelar como emulsificante de pickering

    Unknown journal · 2021-09-15

    Lucas Urbano Jose

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  39. Improved biological performance of ketoprofen using novel modified halloysite clay nanotubes

    Applied Clay Science · 2021-11-30

    Dounia Sid, Milad Baitiche, Lekhmici Arrar, Ferhat Djerboua, Riadh Bourzami, Pierre Alcouffe, Mokhtar Boutahala, Antonio Gil, Laurent David, Marc Le Borgne

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  40. Innovative membrane containing iron-based layered double hydroxide intercalated with phyto therapeutic diterpenoid

    Applied Clay Science · 2021-12-23

    Mariana Pires Figueiredo, Brenda Lini, Fátima García‐Villén, Ana Borrego‐Sánchez, Alessandra Rossi, César Viseras, Vera Regina Leopoldo Constantino

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  41. Fe(III)‐Based Layered Double Hydroxides Carrying Model Naproxenate Anions: Compositional and Structural Aspects

    ChemistrySelect · 2022-01-05

    Mariana Pires Figueiredo, Vanessa R. R. Cunha, J. Cellier, Christine Taviot‐Guého, Vera Regina Leopoldo Constantino

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  42. Anti-Inflammatory and Analgesic Evaluation of a Phytochemical Intercalated into Layered Double Hydroxide

    Pharmaceutics · 2022-04-25

    Viviane Aparecida Guilherme, Vanessa R. R. Cunha, Eneida de Paula, Daniele Ribeiro de Araújo, Vera Regina Leopoldo Constantino

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  43. Limiting content of trivalent iron to form organic-inorganic single-phase layered double hydroxides hybrids by coprecipitation

    Applied Clay Science · 2022-07-21

    Mariana Pires Figueiredo, Eduardo Díaz Suárez, Helena Maria Petrilli, Fabrice Leroux, Christine Taviot‐Guého, Vera Regina Leopoldo Constantino

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  44. Development of Dipeptide N–acetyl–L–cysteine Loaded Nanostructured Carriers Based on Inorganic Layered Hydroxides

    Pharmaceutics · 2023-03-15

    Denise Eulálio, Mariana Pires Figueiredo, Christine Taviot‐Guého, Fabrice Leroux, Cristina Helena dos Reis Serra, Dalva Lúcia Araújo de Faria, Vera Regina Leopoldo Constantino

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  45. Estudo de processo inflamatório articular por espectroscopia Raman: ação de compostos lamelares e detecção de alterações fisiológicas

    Unknown journal · 2023-05-26

    Otávio M. Gil

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  46. Effect of Zn2Cr layered double hydroxide on photocatalytic hydroxylation of terephthalic acid and photodegradation of sodium diclofenac

    Catalysis Today · 2023-07-12

    Anne Raquel Sotiles, Lorrana Vietro Barbosa, Yan Pita Vedovato, Fernando Wypych, Emerson Henrique de Faria

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  47. Layered Double Hydroxide Nanocarriers: Potential Delivery Systems for Mefenamic Acid

    Nanomedicine · 2023-10-01

    Parteek Prasher, Mousmee Sharma

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  48. κ-Carrageenan/sericin polymer matrix modified with different crosslinking agents and thermal crosslinking: Improved release profile of mefenamic acid

    International Journal of Biological Macromolecules · 2024-02-01

    Wedja Timóteo Vieira, Maria Vitória Silva Nicolini, Meuris Gurgel Carlos da Silva, Laura de Oliveira Nascimento, Melissa Gurgel Adeodato Vieira

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  49. Recent Insights and Clinical Status on Novel Mefenamic Acid Nanocarriers for the Treatment of Rheumatoid Arthritis

    Current Nanomaterials · 2024-10-14

    Sunayana Tyagi, Milind Sharad Pande, Mojahidul Islam

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  50. Free-Standing Bacterial Films Reinforced with 2D Layered Double Hydroxide Nanosheets: A Step Towards Living Materials

    SSRN Electronic Journal · 2025-01-01

    Ilya Shlar, Yanna Gurianov, Elena Poverenov

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