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RESEARCH PAPER · Gels · 2025

Machine Learning in Gel-Based Additive Manufacturing: From Material Design to Process Optimization

Zhizhou Zhang, Yaxin Wang, Weiguang Wang

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Machine Learning in Gel-Based Additive Manufacturing: From Material Design to Process OptimizationOriginalManufacturing, Microstructure, and Mechanics of 316L SS Biomaterials by Laser Powder Bed Fusion20Laser additive manufacturing of ultra-high temperature Ta4HfC5 ceramic components10AI-Integrated Micro/Nanorobots for Biomedical Applications: Recent Advances in Design, Fabrication, and Functions27Artificial Intelligence Informed Hydrogel Biomaterials in Additive Manufacturing28Physics-informed neural networks for predicting high-strain-rate energy absorption in additively manufactured lattice materials11From 3D to 6D bioprinting: emerging additive manufacturing technologies for biomedical applications7Food Additive Manufacturing 4.0: integrating innovations in three-dimensional printing and beyond1Multimodal health monitoring and theranostics based on functionalized hydrogels and artificial intelligence2Artificial intelligence & machine learning in hydrogel: Revolutionizing design and optimization – detailed review20Multi-stimuli responsive hydrogels in bone tissue engineering: microenvironmental cues and biofunctional strategies2Predicting the Storage Modulus of Chromium‐Crosslinked Polymer Gels Through Advanced Machine Learning Techniques0Design and Application of Stimuli-Responsive Hydrogels for 4D Printing: A Review of Adaptive Materials in Engineering19Next generation bioprinting with artificial intelligence in the healthcare industry21The Synthetic Extracellular Matrix as a Maestro of the In Vitro Stem Cell Niche: Orchestrating Fate and Function4Tri-domain prediction and optimization of nanocomposite polymers for high-performance 3D printing1Cellulose-Based Conductive Hydrogels: Design Strategies and Applications in Flexible Electronics5Emerging Machine Learning Strategies for Digital Processing and Additive Manufacturing of Advanced Ceramics0Conductive hydrogels: Bridging bioelectrical signal regulation and multitissue regenerative repair in tissue engineering0Microfluidics meets organoids: Kidney and bladder-on-Chip models for preclinical drug delivery assessment2AI-assisted, curvature-aware post-slicing G-code optimization for material-efficient FDM printing0Machine-Learning-Enabled Hydrogel Biosensors for Wearable Health Monitoring5Magnetic Cellulose Nanocrystal Composites: Synthesis, Properties, Applications, and Opportunities1Stimuli‐Responsive Hydrogels for Optical Applications: Mechanisms, Architectures, and Translational Challenges2Collagen and its derivatives in the food industry: A review of sources, extraction, functional properties, and applications1Machine Learning-Based Prediction of Textural Properties and Nonlinear Regulatory Pattern Analysis of 3D-Printed Dough Containing Konjac Glucomannan0A Review on Computational Modeling of Time-Evolving Functionality in 4d Manufacturing: From Smart Materials to Surface-Driven Systems1Construction of Zn2+ Chelated Dodecapeptide Assembled Hydrogel with Bio-Adhesive and Bone Regeneration Functions0Explainable and comparative machine learning models for punching shear prediction in reinforced concrete flat slabs3Gelatin nanogels: a versatile platform for biomedical and therapeutic applications1Machine learning applications to bioactive glasses: From traditional statistical models to cutting-edge deep learning paradigms0Engineering performance of plant protein gels: From molecular design to application-driven functionalities1Functional 4D food printing: engineering smart, stimuli-responsive edible systems for personalized nutrition0Functional Materials for Additive Manufacturing: Materials Design, Processing, and Emerging Applications0AI-Powered Biomaterial Design for Tissue Engineering2Deep learning-driven insights into the multiscale structure-function relationships of starch macromolecules0Artificial intelligence–assisted smart hydrogel bioinks in 3D bioprinting: design, optimization, and construct validation for functional tissue engineering0Sulfate Attack-Induced C-S-H Gel Degradation Mechanism and Machine Learning-Based Strength Prediction of Coal Gangue Aggregate Concrete0Machine learning approaches for optimizing bioprinting processes: A comprehensive review0From Processing to Performance: A Multi-Scale Machine Learning Framework for SBS-Modified Asphalt Gels with Multi-Target Correlation and Explainable AI0Additive manufacturing - an antidote to bottlenecks in tissue engineering and regenerative medicine0Geometric and topological deep learning for predicting thermo-mechanical performance in cold spray deposition process modeling0Machine learning based predictive modelling and optimization for improved mechanical properties of FDM printed polymer parts04D bioprinting in advanced cancer model: technologies, drug delivery, and translational challenges0Laser powder bed fusion of improved yield strength and dense TiC/Cu composite2

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  1. Manufacturing, Microstructure, and Mechanics of 316L SS Biomaterials by Laser Powder Bed Fusion

    Journal of Functional Biomaterials · 2025-07-31

    Zhizhou Zhang, Paul Tarisai Mativenga, Shiqing Huang

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  2. Laser additive manufacturing of ultra-high temperature Ta4HfC5 ceramic components

    Journal of Manufacturing Processes · 2025-08-29

    Zhizhou Zhang, Craig J. Williams, George Maddison, Yang Sha, Menghui Zhu, Dongxu Cheng, Chao Yi Wei, Xiangli Zhong, Zhu Liu, Paul Tarisai Mativenga, Lin Li

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  3. AI-Integrated Micro/Nanorobots for Biomedical Applications: Recent Advances in Design, Fabrication, and Functions

    Biosensors · 2025-12-02

    Prashant Kishor Sharma, Chia‐Yuan Chen

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  4. Artificial Intelligence Informed Hydrogel Biomaterials in Additive Manufacturing

    Gels · 2025-12-06

    Zhizhou Zhang, Zach Z. Tao, Ruiling Du, Runxin Huo, Xiangrui Zheng

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  5. Physics-informed neural networks for predicting high-strain-rate energy absorption in additively manufactured lattice materials

    Progress in Additive Manufacturing · 2025-12-19

    Veera Siva Reddy Bobbili, C. Chandrasekhara Sastry, Jallu Krishnaiah, Arif Rahman, S. Surya Kumar, N.S. Reddy

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  6. From 3D to 6D bioprinting: emerging additive manufacturing technologies for biomedical applications

    Biomedical Materials · 2025-12-22

    Sara Derhambakhsh, Nasrin Salehi, Shirin Changizi, Mehran Solati‐Hashjin

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  7. Food Additive Manufacturing 4.0: integrating innovations in three-dimensional printing and beyond

    Elsevier eBooks · 2026-01-01

    Abdo Hassoun

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  8. Multimodal health monitoring and theranostics based on functionalized hydrogels and artificial intelligence

    Journal of Materials Chemistry B · 2026-01-01

    Tingyu Sun, Shilong Liu, Kun Qian, Shunxiang Li

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  9. Artificial intelligence & machine learning in hydrogel: Revolutionizing design and optimization – detailed review

    Next research. · 2026-01-10

    Ishan Aboti, Nilakshi N. Dhoble, Nitin Padole, Pankaj R. Dhapake, Jagdish Baheti

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  10. Multi-stimuli responsive hydrogels in bone tissue engineering: microenvironmental cues and biofunctional strategies

    Science China Materials · 2026-01-29

    Tingting Yang, Yuemeng Zhu, Junjie Jiao, Jingjie Zhai, Quan Lin

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  11. Predicting the Storage Modulus of Chromium‐Crosslinked Polymer Gels Through Advanced Machine Learning Techniques

    Polymers for Advanced Technologies · 2026-02-01

    Farag M. A. Altalbawy, Raed H. C. Alfilh, Tarak P. Vora, Anupam Yadav, Ramachandra Manjunatha, Rishabh Thakur, B. Angel, Priyadarshi Das, Anup Singh Negi, Muyassar Norberdiyeva, Ahmad Abumalek

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  12. Design and Application of Stimuli-Responsive Hydrogels for 4D Printing: A Review of Adaptive Materials in Engineering

    Gels · 2026-02-02

    Muhammad F. Siddique, Farag Omar, Ali Hassan Al-Marzouqi

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  13. Next generation bioprinting with artificial intelligence in the healthcare industry

    Next Bioengineering · 2026-02-14

    Babita Dhiman, Roopsandeep Bammidi, Mohit Kumar, Sanjay Mavinkere Rangappa, Suchart Siengchin

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  14. The Synthetic Extracellular Matrix as a Maestro of the In Vitro Stem Cell Niche: Orchestrating Fate and Function

    Biomedicines · 2026-02-23

    Subhajit Giri, Pratyush Rajesh

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  15. Tri-domain prediction and optimization of nanocomposite polymers for high-performance 3D printing

    Scientific Reports · 2026-03-31

    Lakshmaiya Natrayan, P. Hari Chandra Prasad, Prabhu Paramasivam, Ramya Maranan, Anand Rajendran, Gemeda Bekele Bacha

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  16. Cellulose-Based Conductive Hydrogels: Design Strategies and Applications in Flexible Electronics

    Gels · 2026-04-29

    Xu Dong, Mizhao Song, Zhihui Sui, Shuzhen Gao, Zhouyuanye Wan, Jianhua Zheng, Hongbin Li

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  17. Emerging Machine Learning Strategies for Digital Processing and Additive Manufacturing of Advanced Ceramics

    International Journal of Applied Ceramic Technology · 2026-04-29

    Sioney Teixeira Monteiro, Isaac A. T. Monteiro, Jose R. Fernández-Gamboa, Yurimiler Leyet

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  18. Conductive hydrogels: Bridging bioelectrical signal regulation and multitissue regenerative repair in tissue engineering

    Sustainable materials and technologies · 2026-05-01

    Jiameng Zhang, Yihan Wang, Chuqiao Wei, Yuemeng Zhu, Xuyan Wei, Sheng Chen, Zhibo Wang, Dongyang Wang, Yanmin Zhou

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  19. Microfluidics meets organoids: Kidney and bladder-on-Chip models for preclinical drug delivery assessment

    Advanced Drug Delivery Reviews · 2026-05-05

    C. Ma, D. Koh, T. Nishimura, Y. Takata, Y. Kameda, R. Negoro, N. Ishiguro, M. Shibuta, Ichiji Namatame, Kazuhiro Tetsuka, Toshikazu Araoka, Minoru Takasato, J. Jang, J. Yoon, R. Yokokawa

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  20. AI-assisted, curvature-aware post-slicing G-code optimization for material-efficient FDM printing

    Journal of King Saud University - Engineering Sciences · 2026-05-11

    Laith Abdullah Al-Juboori

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  21. Machine-Learning-Enabled Hydrogel Biosensors for Wearable Health Monitoring

    Gels · 2026-05-20

    Zhizhou Zhang

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  22. Magnetic Cellulose Nanocrystal Composites: Synthesis, Properties, Applications, and Opportunities

    Nanomaterials · 2026-05-22

    Mohammad Jahid Hasan, Kishore Chand, Esteban E. Ureña-Benavides, Erick S. Vasquez

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  23. Stimuli‐Responsive Hydrogels for Optical Applications: Mechanisms, Architectures, and Translational Challenges

    Aggregate · 2026-05-25

    Andrés Bernal-Ballén, Alexandr Dejneka, Oleg Lunov

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  24. Collagen and its derivatives in the food industry: A review of sources, extraction, functional properties, and applications

    Results in Chemistry · 2026-05-27

    Palanivendhan Murugadoss, Ajay Kumar Karna, Naveen Kumar Rajendran, Shivendu Saxena, Yuvaraja Naik, Trapty Agarwal, Aseel Smerat, Ravikumar Jayabal, K. Kamakshi Priya

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  25. Machine Learning-Based Prediction of Textural Properties and Nonlinear Regulatory Pattern Analysis of 3D-Printed Dough Containing Konjac Glucomannan

    Foods · 2026-06-01

    Wenjun Leng, Yilan Sun, Xie Jianhua, Jie Pang

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  26. A Review on Computational Modeling of Time-Evolving Functionality in 4d Manufacturing: From Smart Materials to Surface-Driven Systems

    Archives of Computational Methods in Engineering · 2026-06-04

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  27. Construction of Zn2+ Chelated Dodecapeptide Assembled Hydrogel with Bio-Adhesive and Bone Regeneration Functions

    Gels · 2026-06-09

    Jun Bai, Lenan Zhuang

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  28. Explainable and comparative machine learning models for punching shear prediction in reinforced concrete flat slabs

    Multiscale and Multidisciplinary Modeling Experiments and Design · 2026-06-10

    Qaim Shah, Irfan Ullah, Waheed Ali Khoso, Fawad Iqbal, Mussa Umali

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  29. Gelatin nanogels: a versatile platform for biomedical and therapeutic applications

    International Journal of Polymeric Materials · 2026-06-19

    Chintan J. Aundhia, Chitrali Talele, Dipali R. Talele, Jagruti L. Desai, Bhupendra Gopalbhai Prajapati

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  30. Machine learning applications to bioactive glasses: From traditional statistical models to cutting-edge deep learning paradigms

    Journal of Non-Crystalline Solids · 2026-06-22

    Amirhossein Moghanian, Ahmet Akif Kızılkurtlu, Mohammad Nasr Esfahani, Arang Pazhouheshgar, Francesco Baino, Ali Akpek, Sirus Safaee

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  31. Engineering performance of plant protein gels: From molecular design to application-driven functionalities

    Food Chemistry · 2026-06-26

    Divya Singh Chauhan, Ram Prasad Bebartta, Akshit Kapila, Hamid, Mehnaza Manzoor

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  32. Functional 4D food printing: engineering smart, stimuli-responsive edible systems for personalized nutrition

    Food Production Processing and Nutrition · 2026-07-07

    Rokaia R. Abdelsalam, Mohamed Fawzy Ramadan

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  33. Functional Materials for Additive Manufacturing: Materials Design, Processing, and Emerging Applications

    Nanomaterials · 2026-07-17

    Rashid Dallaev

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  34. AI-Powered Biomaterial Design for Tissue Engineering

    Artificial intelligence · 2026-07-20

    Eghosasere Egbon

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  35. Deep learning-driven insights into the multiscale structure-function relationships of starch macromolecules

    Journal of Cereal Science · 2026-07-27

    Yang Xuexin, Cejun Li, Yue Han, W LI, Haohui Han, Ying Sun

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  36. Artificial intelligence–assisted smart hydrogel bioinks in 3D bioprinting: design, optimization, and construct validation for functional tissue engineering

    Frontiers in Bioengineering and Biotechnology · 2026-08-10

    Siyuan Zhang, Dingwen Liang, Yingying Lei, Yuxi Luo, Rui Shi

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  37. Sulfate Attack-Induced C-S-H Gel Degradation Mechanism and Machine Learning-Based Strength Prediction of Coal Gangue Aggregate Concrete

    Gels · 2026-08-11

    Shuanghua He, Ruicong Han, Junfeng Guan, Ying Hao, Li Zhao, Yafei Jing

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  38. Machine learning approaches for optimizing bioprinting processes: A comprehensive review

    Next Materials · 2026-08-22

    Sachin Venu Jaya, Dileep Chekkaramkodi, Haider Butt

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  39. From Processing to Performance: A Multi-Scale Machine Learning Framework for SBS-Modified Asphalt Gels with Multi-Target Correlation and Explainable AI

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    Zongyuan Wu, Xiaoyu Ma, Mengxin Qiu, Chenze Fang, Weizhan Liu, Decai Wang

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  40. Additive manufacturing - an antidote to bottlenecks in tissue engineering and regenerative medicine

    Frontiers in Bioengineering and Biotechnology · 2026-09-08

    Yifan Li, Fabian Tribukait‐Riemenschneider, Yawei Gu, Venkatram Prasad Shastri

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  41. Geometric and topological deep learning for predicting thermo-mechanical performance in cold spray deposition process modeling

    Discover Informatics · 2026-09-09

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  42. Machine learning based predictive modelling and optimization for improved mechanical properties of FDM printed polymer parts

    Colloid & Polymer Science · 2026-09-14

    Avishek Samanta, Kuntal Maji

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  43. 4D bioprinting in advanced cancer model: technologies, drug delivery, and translational challenges

    Journal of Biomaterials Science Polymer Edition · 2026-09-18

    Santoshini Nayak, Snehamayee Mohapatra, Rajat Kumar Kar

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  44. Laser powder bed fusion of improved yield strength and dense TiC/Cu composite

    Journal of Manufacturing Processes · 2026-09-23

    Zhizhou Zhang, Tianxiao Si, Yue Kong, Chunjiang Fu, Hasan Hüseyin HAYAT, Biao Cai

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