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RESEARCH PAPER · Analytical Chemistry · 2024

Nanocrystalline Porous Materials for Chiral Separation: Synthesis, Mechanisms, and Applications

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Nanocrystalline Porous Materials for Chiral Separation: Synthesis, Mechanisms, and ApplicationsOriginalRecent progress of chiral metal–organic frameworks in enantioselective separation and detection19Synergistic enantioseparation system based on a novel nanomaterial synthesized by chiral metal–organic framework and chiral molecularly imprinted polymer in capillary electrochromatography12Proportionally controlled dual-chiral covalent organic frameworks via thiol-ene click reaction for efficient enantioseparation16Homochiral metal–organic framework membranes synthesized using a nonstochastic chiral bias for enhanced enantioselective separation10Recent developments and applications of solid membrane in chiral separation12Chiral electrokinetic chromatography using dual pseudo-stationary phases: SBE-β-CD with hydrophobic (deep) eutectic solvents versus micelles and ionic liquids3Facile fabrication of tailored Pepsin@COF nanobiohybrid platform for high-performance chiral separation13A general strategy for constructing covalent organic frameworks chiral membranes with a wide range of enantio-selectors for efficient separations6Sustainable methods for the synthesis of chiral nanomaterials49Pepsin-Functionalized Covalent Organic Framework Chiral Membrane Assembly via a Vacuum-Assisted Process for Chiral Separation9Edge-centred chirality-induced enantiopure square-like sulfonylcalix[4]arene-{Co ii 16 } cages for selective (+)-/(−)-α-pinene adsorption1Lipase-based HKUST-1 (Cu) biocomposites as chiral stationary phase for enantiomer separation in capillary electrochromatography5Chiral separations in capillary electrophoresis with betaine:urea as a major component of a mixed aqueous-deep eutectic solvent4Constructing a composite interface on in situ grown MOF scaffolds for efficient separation of D,L-amino acids via chiral ligand-exchange capillary electrochromatography2In Situ Preparation of Hydrophilic Chiral Covalent Organic Framework Membranes for Enantioseparation of Drugs3Norepinephrine-coated defect-engineered chiral MOF enables synergistic enantioseparation in capillary electrochromatography3Enantioselective recognition-driven antibacterial activity by a multifunctional MOF-based chiral nanozyme1Chiral Surface Engineering–Boosted Catalytic Activity of CuO Nanomaterials on Luminol–H2O2 Chemiluminescence for Facile Discrimination of Alanine Enantiomers0Enantioselective dispersive solid-phase extraction of chiral drugs and amino acids using a homochiral Zn-based MOF: Mechanistic insights into chiral recognition0Chiral HPLC in biomedical and pharmaceutical analysis: Method development challenges and application–oriented strategies0Adaptive Cinchona Alkaloid-Derived Organoboron Crystalline Sponges Enable Enantioseparation of Weakly Interacting Molecules0

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  1. Recent progress of chiral metal–organic frameworks in enantioselective separation and detection

    Microchimica Acta · 2024-10-02

    Huiting Chen, Ling Xia, Gongke Li

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  2. Synergistic enantioseparation system based on a novel nanomaterial synthesized by chiral metal–organic framework and chiral molecularly imprinted polymer in capillary electrochromatography

    Microchimica Acta · 2024-10-21

    Pandeng Miao, Dongyang Zhu, Shuaijing Du, Yingxiang Du

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  3. Proportionally controlled dual-chiral covalent organic frameworks via thiol-ene click reaction for efficient enantioseparation

    Talanta · 2024-11-01

    Yifang Liao, Liqin Cao, Qixuan Mu, Jiale Zhang, Ruijun Li, Yibing Ji

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  4. Homochiral metal–organic framework membranes synthesized using a nonstochastic chiral bias for enhanced enantioselective separation

    Journal of Materials Chemistry A · 2025-01-01

    Boxun Li, Yue Feng, Dan Zhou, Maochun Yang, Dan Li, Shuai Zhang, Jingru Fu, Teng Ben

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  5. Recent developments and applications of solid membrane in chiral separation

    Journal of Chromatography A · 2025-01-02

    Li Ge, Xinyu Li, Gege Zhu, Bing Niu, Qin Chen, Dan Zhong, Xiaodong Sun

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  6. Chiral electrokinetic chromatography using dual pseudo-stationary phases: SBE-β-CD with hydrophobic (deep) eutectic solvents versus micelles and ionic liquids

    Separation and Purification Technology · 2025-06-07

    Song Xue, Yu Xu, Sihui Ding, Haoxiang Meng, Xiaodong Sun, Qi Zhang

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  7. Facile fabrication of tailored Pepsin@COF nanobiohybrid platform for high-performance chiral separation

    Analytica Chimica Acta · 2025-06-21

    Jiale Zhang, Qixuan Mu, Xinyue Li, Yifang Liao, Yifang Liao, Yibing Ji, Yibing Ji

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  8. A general strategy for constructing covalent organic frameworks chiral membranes with a wide range of enantio-selectors for efficient separations

    Microchimica Acta · 2025-06-24

    Qixuan Mu, Yuting Chen, Xiuxiu Li, Yibing Ji

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  9. Sustainable methods for the synthesis of chiral nanomaterials

    Cell Reports Physical Science · 2025-08-01

    Tingting Hong, Jiaqi Guan, Wenhu Zhou, Songwen Tan, Zhiqiang Cai

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  10. Pepsin-Functionalized Covalent Organic Framework Chiral Membrane Assembly via a Vacuum-Assisted Process for Chiral Separation

    Analytical Chemistry · 2025-09-23

    Xiuxiu Li, Qixuan Mu, Ruijun Li, Yibing Ji

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  11. Edge-centred chirality-induced enantiopure square-like sulfonylcalix[4]arene-{Co ii 16 } cages for selective (+)-/(−)-α-pinene adsorption

    Chemical Communications · 2025-12-15

    Ilia D. Shutilov, Pavel A. Volodin, Alexander S. Ovsyannikov, Ilya M. Zinoviev, Vladimir Yu. Guskov, Daut R. Islamov, Timur A. Mukhametzyanov, Mei‐Jin Lin, Pavel V. Dorovatovskii, Georgy S. Peters, Elizaveta S. Kulikova, Vladimir A. Burilov, Svetlana E. Solovieva, Igor S. Antipin

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  12. Lipase-based HKUST-1 (Cu) biocomposites as chiral stationary phase for enantiomer separation in capillary electrochromatography

    Analytica Chimica Acta · 2026-01-14

    Mengxue Tang, Jiale Zhang, Qixuan Mu, Keyan Chen, Yibing Ji

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  13. Chiral separations in capillary electrophoresis with betaine:urea as a major component of a mixed aqueous-deep eutectic solvent

    Separation and Purification Technology · 2026-01-17

    Qing Wu, Zanhao Huang, Song Xue, Haoxiang Meng, Shumei Liu, Xingyan Wang, Qi Zhang

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  14. Constructing a composite interface on in situ grown MOF scaffolds for efficient separation of D,L-amino acids via chiral ligand-exchange capillary electrochromatography

    Talanta · 2026-02-02

    Dan Wang, Panpan Chen, Qin Huang, Yan Ma, Xueping Tao, Yuanmin Gong, Jiaping Cui, Yang Zhou, Zhining Xia, Qifeng Fu

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  15. In Situ Preparation of Hydrophilic Chiral Covalent Organic Framework Membranes for Enantioseparation of Drugs

    ACS Applied Materials & Interfaces · 2026-02-13

    Yuting Chen, Qixuan Mu, Keyan Chen, Yibing Ji

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  16. Norepinephrine-coated defect-engineered chiral MOF enables synergistic enantioseparation in capillary electrochromatography

    Talanta · 2026-03-23

    Zhenhua Zhai, Chunyan Guo, Le Liang, Shuaijing Du, Yingxiang Du

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  17. Enantioselective recognition-driven antibacterial activity by a multifunctional MOF-based chiral nanozyme

    Chemical Engineering Journal · 2026-05-12

    Xiaohui Niu, Jianying Zhang, Yue Wang, Zhe Wang, Xing Yang, Hui Li, Y N Li, Kunjie Wang

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  18. Chiral Surface Engineering–Boosted Catalytic Activity of CuO Nanomaterials on Luminol–H2O2 Chemiluminescence for Facile Discrimination of Alanine Enantiomers

    Analytical Chemistry · 2026-07-31

    Pengfei Wang, Zihui Feng, Ling Zhang, Chunli Xu, Baoxin Li

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  19. Enantioselective dispersive solid-phase extraction of chiral drugs and amino acids using a homochiral Zn-based MOF: Mechanistic insights into chiral recognition

    Separation and Purification Technology · 2026-08-21

    Shiyu Zhang, Zhiruo Li, Jia Tong, Xingxing Shi, Yue Xu, lijuan Zhang, Haikuan Yuan, Yan Zhang, J J Lu

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  20. Chiral HPLC in biomedical and pharmaceutical analysis: Method development challenges and application–oriented strategies

    Journal of Chromatography B · 2026-09-02

    Mihajlo Jakanovski, Mila Č. Lazović, Mirjana D. Mosić, Marko D. Jović, Milica S. Jankov, Sandra B. Šegan

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  21. Adaptive Cinchona Alkaloid-Derived Organoboron Crystalline Sponges Enable Enantioseparation of Weakly Interacting Molecules

    Journal of the American Chemical Society · 2026-10-02

    Maximilian Rajski, Michał Terlecki, Iwona Justyniak, Arkadiusz Kornowicz, Michał Krzysztof Leszczyński, Mikołaj Cieślak, Janusz Lewiński

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