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RESEARCH PAPER · eLife · 2020

COVID-19 research risks ignoring important host genes due to pre-established research patterns

Thomas Stoeger, Luı́s A. Nunes Amaral

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COVID-19 research risks ignoring important host genes due to pre-established research patternsOriginalHow Geneticists Contribute to Understanding of Covid-19 Disease Pathogenicity6Searching and Analyzing Patent-Relevant Information for Evaluating COVID-19 Innovation3Adaptability and the Pivot Penalty in Science13Meta-Analysis of Gene Popularity: Less Than Half of Gene Citations Stem from Gene Regulatory Networks4Interpretable network propagation with application to expanding the repertoire of human proteins that interact with SARS-CoV-28Systematic Review of Functional Pathways and Methods for COVID-19 Modelling0The characteristics of early-stage research into human genes are substantially different from subsequent research13COVID-19: impact on Public Health and hypothesis-driven investigations on genetic susceptibility and severity11An open invitation to the Understudied Proteins Initiative51Mass spectrometry‐based high‐throughput proteomics and its role in biomedical studies and systems biology132Protection of the human gene research literature from contract cheating organizations known as research paper mills44Additional file 3 of Did the early full genome sequencing of yeast boost gene function discovery?0Meta-Research: understudied genes are lost in a leaky pipeline between genome-wide assays and reporting of results5The proteomic landscape of genome-wide genetic perturbations82Ageing restructures the transcriptome of the hypothalamic supraoptic nucleus and alters the response to dehydration4Did the early full genome sequencing of yeast boost gene function discovery?3Cellular control of protein levels: A systems biology perspective42Meta-Research: understudied genes are lost in a leaky pipeline between genome-wide assays and reporting of results0Meta-Research: Understudied genes are lost in a leaky pipeline between genome-wide assays and reporting of results18Meta-Research: understudied genes are lost in a leaky pipeline between genome-wide assays and reporting of results0Meta-Research: Understudied genes are lost in a leaky pipeline between genome-wide assays and reporting of results2Integrating Large-Scale Protein Structure Prediction into Human Genetics Research13The Interleukin-6 gene variants may protect against SARS-CoV-2 infection and the severity of COVID-19: a case-control study in a Moroccan population10A graph theoretical approach to experimental prioritization in genome-scale investigations4Funding priorities and health outcomes in Danish medical research4Scientific exploration outlasts industrial momentum and sustains innovation in genetic research: survey of 20 million papers and patents0The pivot penalty in research38A comparative approach for selecting orthologous candidate genes in genome-wide association studies across multiple species3

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28 direct citing papers saved.

  1. How Geneticists Contribute to Understanding of Covid-19 Disease Pathogenicity

    Acta Endocrinologica (Bucharest) · 2020-01-01

    F Grigorescu

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  2. Searching and Analyzing Patent-Relevant Information for Evaluating COVID-19 Innovation

    SSRN Electronic Journal · 2020-01-01

    Luca Falciola, Massimo Barbieri

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  3. Adaptability and the Pivot Penalty in Science

    SSRN Electronic Journal · 2021-01-01

    Ryan Hill, Yian Yin, Carolyn Stein, Dashun Wang, Benjamin F. Jones

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  4. Meta-Analysis of Gene Popularity: Less Than Half of Gene Citations Stem from Gene Regulatory Networks

    Genes · 2021-02-23

    Ionut Sebastian Mihai, Debojyoti Das, Gabija Maršalkaite, Johan Henriksson

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  5. Interpretable network propagation with application to expanding the repertoire of human proteins that interact with SARS-CoV-2

    GigaScience · 2021-12-01

    Jeffrey Law, Kyle Akers, Nure Tasnina, Catherine Marin Della Santina, Shay Deutsch, Meghana Kshirsagar, Judith Klein‐Seetharaman, Mark E. Crovella, Padmavathy Rajagopalan, Simon Kasif, T. M. Murali

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  6. Systematic Review of Functional Pathways and Methods for COVID-19 Modelling

    Baltic Journal of Modern Computing · 2022-01-01

    Ramunė Vaišnorė, Gabija Mazur, Violeta Mikštienė, Audronė Jakaitienė

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  7. The characteristics of early-stage research into human genes are substantially different from subsequent research

    PLoS Biology · 2022-01-06

    Thomas Stoeger, Luı́s A. Nunes Amaral

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  8. COVID-19: impact on Public Health and hypothesis-driven investigations on genetic susceptibility and severity

    Immunogenetics · 2022-03-29

    Susana David, Guillermo Dorado, Elsa Leclerc Duarte, Stéphanie David-Bosne, João M. Trigueiro-Louro, Helena Rebelo‐de‐Andrade

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  9. An open invitation to the Understudied Proteins Initiative

    Nature Biotechnology · 2022-05-09

    Georg Kustatscher, Tom Collins, Anne‐Claude Gingras, Tiannan Guo, Henning Hermjakob, Trey Ideker, Kathryn Susan Lilley, Emma K. Lundberg, Edward M. Marcotte, Markus Ralser, Juri Rappsilber

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  10. Mass spectrometry‐based high‐throughput proteomics and its role in biomedical studies and systems biology

    PROTEOMICS · 2022-11-09

    Christoph B. Messner, Vadim Petrovich Demichev, Ziyue Wang, Johannes Hartl, Georg Kustatscher, Michael Mülleder, Markus Ralser

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  11. Protection of the human gene research literature from contract cheating organizations known as research paper mills

    Nucleic Acids Research · 2022-11-15

    Jennifer Anne Byrne, Yasunori Park, Reese A. K. Richardson, Pranujan Pathmendra, Mengyi Sun, Thomas Stoeger

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  12. Additional file 3 of Did the early full genome sequencing of yeast boost gene function discovery?

    Figshare · 2023-01-01

    Erwin Tantoso, Birgit Eisenhaber, Swati Sinha, Lars Juhl Jensen, Frank Eisenhaber

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  13. Meta-Research: understudied genes are lost in a leaky pipeline between genome-wide assays and reporting of results

    bioRxiv (Cold Spring Harbor Laboratory) · 2023-03-01

    Reese A. K. Richardson, Heliodoro Tejedor Navarro, Luı́s A. Nunes Amaral, Thomas Stoeger

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  14. The proteomic landscape of genome-wide genetic perturbations

    Cell · 2023-04-01

    Christoph B. Messner, Vadim Petrovich Demichev, Julia Muenzner, Simran Kaur Aulakh, Natalie Barthel, Annika Röhl, Lucía Herrera-Domínguez, Anna-Sophia Egger, Stephan Kamrad, Jing Hou, Guihong Tan, Oliver Lemke, Enrica Calvani, Łukasz Szyrwiel, Michael Mülleder, Kathryn Susan Lilley, Charles M. Boone, Georg Kustatscher, Markus Ralser

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  15. Ageing restructures the transcriptome of the hypothalamic supraoptic nucleus and alters the response to dehydration

    npj Aging · 2023-06-01

    Ghadir Elsamad, André S. Mecawi, Audrys G. Pauža, Benjamin T. Gillard, Alex R. Paterson, Victor J. Duque, Olivera Šarenac, Nina Japundžić‐Žigon, Mingkwan Greenwood, Michael Paul Greenwood, David Murphy

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  16. Did the early full genome sequencing of yeast boost gene function discovery?

    Biology Direct · 2023-08-14

    Erwin Tantoso, Birgit Eisenhaber, Swati Sinha, Lars Juhl Jensen, Frank Eisenhaber

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  17. Cellular control of protein levels: A systems biology perspective

    PROTEOMICS · 2023-11-27

    Victoria Munro, Van C. Kelly, Christoph B. Messner, Georg Kustatscher

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  18. Meta-Research: understudied genes are lost in a leaky pipeline between genome-wide assays and reporting of results

    eLife · 2023-12-15

    Reese A. K. Richardson, Heliodoro Tejedor Navarro, Luı́s A. Nunes Amaral, Thomas Stoeger

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  19. Meta-Research: Understudied genes are lost in a leaky pipeline between genome-wide assays and reporting of results

    eLife · 2023-12-15

    Reese A. K. Richardson, Heliodoro Tejedor Navarro, Luı́s A. Nunes Amaral, Thomas Stoeger

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  20. Meta-Research: understudied genes are lost in a leaky pipeline between genome-wide assays and reporting of results

    eLife · 2024-03-12

    Reese A. K. Richardson, Heliodoro Tejedor Navarro, Luı́s A. Nunes Amaral, Thomas Stoeger

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  21. Meta-Research: Understudied genes are lost in a leaky pipeline between genome-wide assays and reporting of results

    eLife · 2024-03-28

    Reese A. K. Richardson, Heliodoro Tejedor Navarro, Luı́s A. Nunes Amaral, Thomas Stoeger

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  22. Integrating Large-Scale Protein Structure Prediction into Human Genetics Research

    Annual Review of Genomics and Human Genetics · 2024-04-15

    Miguel Correa Marrero, Jürgen Jänes, Delora Baptista, Pedro Beltrão

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  23. The Interleukin-6 gene variants may protect against SARS-CoV-2 infection and the severity of COVID-19: a case-control study in a Moroccan population

    BMC Medical Genomics · 2024-05-23

    Rachid Noureddine, Hanâ Baba, Safaa Aqillouch, Karima Abounouh, Oumaima Laazaazia, Mohcine Elmessaoudi-Idrissi, Fatima-Zohra Bahmani, Ikram‐Allah Tanouti, Ahd Ouladlahsen, M’hammed Sarih, Hind Dehbi, Sayeh Ezzikouri

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  24. A graph theoretical approach to experimental prioritization in genome-scale investigations

    Mammalian Genome · 2024-08-27

    Stephen K. Grady, Kevin A. Peterson, Stephen A. Murray, Erich J. Baker, Michael Allen Langston, Elissa J. Chesler

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  25. Funding priorities and health outcomes in Danish medical research

    Social Science & Medicine · 2024-09-14

    Emil Bargmann Madsen, Jens Peter Andersen

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  26. Scientific exploration outlasts industrial momentum and sustains innovation in genetic research: survey of 20 million papers and patents

    bioRxiv (Cold Spring Harbor Laboratory) · 2025-02-18

    Junghun Chae, WooJoong Kim, Woo Jin Jung, Dawoon Jeong, Roktaek Lim, Manoj Chamlagain, Giju Jung, Juneil Jang, Jae Won Lee, Nam Kyu Kang, Kwangryul Baek, Jonghyeok Shin, Ye-Gi Lee, Hyun Gi Koh, Chanwoo Kim, Sangdo Yook, Allen Ka Loon Cheung, Yong‐Su Jin, Hyejin Youn, Pan‐Jun Kim, Cheol-Min Ghim

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  27. The pivot penalty in research

    Nature · 2025-05-28

    Ryan Hill, Yian Yin, Carolyn Stein, Xizhao Wang, Dashun Wang, Benjamin F. Jones

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  28. A comparative approach for selecting orthologous candidate genes in genome-wide association studies across multiple species

    PLANT PHYSIOLOGY · 2026-05-22

    Lauren Whitt, Elizabeth H. Mahood, Greg Ziegler, Collin Luebbert, Jason D. Gillman, Gareth John Norton, Adam H. Price, David E. Salt, Brian P. Dilkes, Ivan R. Baxter

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