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RESEARCH PAPER · International Journal of Nanomedicine · 2016

Anionic clay as the drug delivery vehicle: tumor targeting function of layered double hydroxide-methotrexate nanohybrid in C33A orthotopic cervical cancer model

Jin‐Ho Choy, Goeun Choi, Piao Huiyan, Zeid A. ALOthman, Ajayan Vinu, Chae‐Ok Yun

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Anionic clay as the drug delivery vehicle: tumor targeting function of layered double hydroxide-methotrexate nanohybrid in C33A orthotopic cervical cancer modelOriginalEnabling Nanohybrid Drug Discovery through the Soft Chemistry Telescope27Magnesium, zinc and calcium aluminium layered double hydroxide-drug nanohybrids: A comprehensive study80Pharmacogenomics of genes involved in antifolate drug response and toxicity in osteosarcoma19Clay–Polymer Nanocomposites for Controlled Drug Release12Time-resolved Fluorescent Detection for Glucose Using a Complex of Luminescent Layered Titanates and Enzymes5Highly Condensed Boron Cage Cluster Anions in 2D Carrier and Its Enhanced Antitumor Efficiency for Boron Neutron Capture Therapy47Layered double hydroxide using hydrothermal treatment: morphology evolution, intercalation and release kinetics of diclofenac sodium32Synergetic co-immobilization of SeO 4 2− and Sr 2+ from aqueous solution onto multifunctional graphene oxide and carbon-dot based layered double hydroxide nanocomposites and their mechanistic investigation26Advanced Inorganic Nanosystems for Skin Drug Delivery53Emerging nanomaterials with advanced drug delivery functions; focused on methotrexate delivery922D Nanostructured Metal Hydroxides with Gene Delivery and Theranostic Functions; A Comprehensive Review58Stabilization of antioxidant gallate in layered double hydroxide by exfoliation and reassembling reaction23Optimization of Formulations Consisting of Layered Double Hydroxide Nanoparticles and Small Interfering RNA for Efficient Knockdown of the Target Gene24Determination of half maximal inhibitory concentration of CaAl layered double hydroxide on cancer cells and its role in the apoptotic pathway33Alendronate-Anionic Clay Nanohybrid for Enhanced Osteogenic Proliferation and Differentiation21Modifying layered double hydroxide nanoparticles for tumor imaging and therapy19Vectorized Clay Nanoparticles in Therapy and Diagnosis15Advances in Therapeutic Implications of Inorganic Drug Delivery Nano-Platforms for Cancer84Passive and active targeting strategies in hybrid layered double hydroxides nanoparticles for tumor bioimaging and therapy33Chlorogenic acid intercalated Gadolinium–Zinc/Aluminium layered double hydroxide and gold nanohybrid for MR imaging and drug delivery49Recent advancements in two‐dimensional nanomaterials for drug delivery66An in vitro comparative study of layered-double hydroxide nanoconjugate in the delivery of small interference and short-hairpin ribonucleic acid6Chemisorption and sustained release of cefotaxime between a layered double hydroxide and polyvinyl alcohol nanofibers for enhanced efficacy against second degree burn wound infection31Cross-sectional characterization of the conversion layer formed on AA2024-T3 by a lithium-leaching coating21Nano-clays as Potential Pseudo-antibodies for COVID-1927In vitro cytotoxicity studies of smart pH-sensitive lamivudine-loaded CaAl-LDH magnetic nanoparticles against Mel-Rm and A-549 cancer cells14Surface-functionalized layered double hydroxide nanocontainers as bile acid sequestrants for lowering hyperlipidemia15Recent progress in layered double hydroxides as a cancer theranostic nanoplatform39New insights on the expediency of Egyptian organoclays to suppress corrosiveness of acidic-produced water in Abu-Rudeis oilfield, South Sinai, by removal of scale-forming cations and sulfate-reducing bacteria: Is there a direct link to clay lamellar ordering?2Homogeneous Incorporation of Gallium into Layered Double Hydroxide Lattice for Potential Radiodiagnostics: Proof-of-Concept7Antibacterial activity and physicochemical characterization of calcium-aluminium-ciprofloxacin-layered double hydroxide25Functional Nanomaterials and their 2D and 3D Fabrications for Drug Delivery Applications2Melanoma treatment via non-specific adhesion of cancer cells using charged nano-clays in pre-clinical studies20Green clay ceramics as potential nanovehicles for drug delivery applications162D Nanosheets—A New Class of Therapeutic Formulations against Cancer25A review on the current progress of layered double hydroxide application in biomedical sectors21Orally administered niclosamide-based organic/inorganic hybrid suppresses SARS-CoV-2 infection2Release behavior and cytotoxicity of captopril-intercalated layered double hydroxide for an antihypertensive drug delivery system8A comprehensive review on methotrexate containing nanoparticles; an appropriate tool for cancer treatment29pH-Responsive Inorganic/Organic Nanohybrids System for Controlled Nicotinic Acid Drug Release11Bio-Inorganic Layered Double Hydroxide Nanohybrids in Photochemotherapy: A Mini Review18Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging59Advancements in Layered Double Hydroxide-Based Chemotherapeutic Nanosystems for Cancer Treatment6Layered double hydroxides - poloxamer 188 nanocomposites based on exfoliation reassembling for improved cellular uptake and controlled delivery of methotrexate2The Next Generation COVID‐19 Antiviral; Niclosamide‐Based Inorganic Nanohybrid System Kills SARS‐CoV‐217Layered double hydroxides and their tailored hybrids/composites: Progressive trends for delivery of natural/synthetic-drug/cosmetic biomolecules44Toward Development of a Plate Discrete Element Method: Geometry and Kinematics2Emerging Multifunctional Carbon‐Nanomaterial‐Based Biosensors for Cancer Diagnosis57Nanoarchitectonics of CTAB-modified kanemite as carrier of methotrexate11A predictive model for calculating the electrostatic intercalation efficiency of methotrexate-loaded laponite dependent on clay concentration and pH built from binding constants2Mechanochemical Loading of Doxorubicin on the Surface of Magnesium and Zinc-Based Layered Double Hydroxides1Saponin Gallate-Loaded Gd-Doped Zinc–Gallium Layered Double Hydroxides (Zn/Ga@Gd-LDH) Nanocarrier for Attenuating NF-κB-Mediated Inflammation4Therapies and nanotherapies for cervical cancer (Review)4

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  1. Enabling Nanohybrid Drug Discovery through the Soft Chemistry Telescope

    Industrial & Engineering Chemistry Research · 2016-10-11

    Goeun Choi, Huiyan Piao, Myung Hun Kim, Jin‐Ho Choy

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  2. Magnesium, zinc and calcium aluminium layered double hydroxide-drug nanohybrids: A comprehensive study

    Applied Clay Science · 2016-10-17

    Suman Saha, Sayantan Ray, Rituparna Acharya, Tapan K. Chatterjee, Jui Chakraborty

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  3. Pharmacogenomics of genes involved in antifolate drug response and toxicity in osteosarcoma

    Expert Opinion on Drug Metabolism & Toxicology · 2016-10-19

    Claudia Maria Hattinger, Elisa Tavanti, Marilù Fanelli, Serena Vella, Piero Picci, Massimo Serra

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  4. Clay–Polymer Nanocomposites for Controlled Drug Release

    Elsevier eBooks · 2017-01-01

    Sorina Alexandra Gȃrea, Anda I. Voicu, Horia Iovu

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  5. Time-resolved Fluorescent Detection for Glucose Using a Complex of Luminescent Layered Titanates and Enzymes

    Analytical Sciences · 2017-09-01

    Yuki Sakaguchi, Tomoka Minamikawa, Mayuko Yamamuro, Tadayuki Tsujita, Toshihisa Ueda, Kai Kamada, Nobuaki Soh

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  6. Highly Condensed Boron Cage Cluster Anions in 2D Carrier and Its Enhanced Antitumor Efficiency for Boron Neutron Capture Therapy

    Advanced Functional Materials · 2017-11-07

    Goeun Choi, Ie‐Rang Jeon, Huiyan Piao, Jin‐Ho Choy

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  7. Layered double hydroxide using hydrothermal treatment: morphology evolution, intercalation and release kinetics of diclofenac sodium

    Frontiers of Materials Science · 2017-11-08

    Mathew Joy, Srividhya J. Iyengar, Jui Chakraborty, Swapankumar Ghosh

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  8. Synergetic co-immobilization of SeO 4 2− and Sr 2+ from aqueous solution onto multifunctional graphene oxide and carbon-dot based layered double hydroxide nanocomposites and their mechanistic investigation

    Journal of Materials Chemistry A · 2018-01-01

    Paulmanickam Koilraj, Yuta Kamura, Keiko Sasaki

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  9. Advanced Inorganic Nanosystems for Skin Drug Delivery

    The Chemical Record · 2018-01-05

    Esperanza Carazo, Ana Borrego‐Sánchez, Fátima García‐Villén, Rita Sánchez‐Espejo, Pilar Cerezo, Carola Aguzzi, César Viseras

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  10. Emerging nanomaterials with advanced drug delivery functions; focused on methotrexate delivery

    Coordination Chemistry Reviews · 2018-01-29

    Goeun Choi, Tae-Hyun Kim, Jae‐Min Oh, Jin‐Ho Choy

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  11. 2D Nanostructured Metal Hydroxides with Gene Delivery and Theranostic Functions; A Comprehensive Review

    The Chemical Record · 2018-02-08

    Goeun Choi, Sairan Eom, Ajayan Vinu, Jin‐Ho Choy

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  12. Stabilization of antioxidant gallate in layered double hydroxide by exfoliation and reassembling reaction

    Solid State Sciences · 2018-04-03

    Kanakappan M. Ansy, Ji Hee Lee, Huiyan Piao, Goeun Choi, Jin‐Ho Choy

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  13. Optimization of Formulations Consisting of Layered Double Hydroxide Nanoparticles and Small Interfering RNA for Efficient Knockdown of the Target Gene

    ACS Omega · 2018-05-02

    Yanheng Wu, Wenyi Gu, Chen Chen, Son Trong, Zhi Ping Xu

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  14. Determination of half maximal inhibitory concentration of CaAl layered double hydroxide on cancer cells and its role in the apoptotic pathway

    Applied Clay Science · 2018-11-02

    Arnab Bhattacharjee, Sk. Hasanur Rahaman, Suman Saha, Monisha Chakraborty, Jui Chakraborty

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  15. Alendronate-Anionic Clay Nanohybrid for Enhanced Osteogenic Proliferation and Differentiation

    Journal of Korean Medical Science · 2019-01-01

    Huiyan Piao, Myung Hun Kim, Meiling Cui, Goeun Choi, Jin‐Ho Choy

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  16. Modifying layered double hydroxide nanoparticles for tumor imaging and therapy

    Clays and Clay Minerals · 2019-02-15

    Li Li, Bei Li, Wenyi Gu, Zhi Ping Xu

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  17. Vectorized Clay Nanoparticles in Therapy and Diagnosis

    Clays and Clay Minerals · 2019-02-15

    Goeun Choi, Huiyan Piao, Sairan Eom, Jin‐Ho Choy

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  18. Advances in Therapeutic Implications of Inorganic Drug Delivery Nano-Platforms for Cancer

    International Journal of Molecular Sciences · 2019-02-22

    Safia Naz, Muhammad Shamoon, Rui Wang, Li Zhang, Juan Zhou, Jinghua Chen

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  19. Passive and active targeting strategies in hybrid layered double hydroxides nanoparticles for tumor bioimaging and therapy

    Applied Clay Science · 2019-07-17

    Karina Nava-Andrade, Ana María Puebla‐Pérez, Gregório Guadalupe Carbajal Arízaga

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  20. Chlorogenic acid intercalated Gadolinium–Zinc/Aluminium layered double hydroxide and gold nanohybrid for MR imaging and drug delivery

    Materials Chemistry and Physics · 2019-09-30

    Muhammad Sani Usman, Mohd Zobir Hussein, Aminu Umar Kura, Sharida Fakurazi, Mas Jaffri Masarudin, Fathinul Fikri Ahmad Saad

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  21. Recent advancements in two‐dimensional nanomaterials for drug delivery

    Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · 2019-10-25

    Xuan Mei, Tingting Hu, Yingjie Wang, Xisheng Weng, Ruizheng Liang, Min Wei

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  22. An in vitro comparative study of layered-double hydroxide nanoconjugate in the delivery of small interference and short-hairpin ribonucleic acid

    Bulletin of Materials Science · 2019-12-17

    Rituparna Acharya, Monisha Chakraborty, Jui Chakraborty

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  23. Chemisorption and sustained release of cefotaxime between a layered double hydroxide and polyvinyl alcohol nanofibers for enhanced efficacy against second degree burn wound infection

    RSC Advances · 2020-01-01

    Maha B. Abd Elhaleem, Ahmed A. Farghali, Ahmed A. G. El‐Shahawy, Fatma I. Abo El‐Ela, Zienab E. Eldine, Rehab Khalid Mahmoud

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  24. Cross-sectional characterization of the conversion layer formed on AA2024-T3 by a lithium-leaching coating

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    Ali Kosari, Peter Visser, Frans D. Tichelaar, Santhana Eswara, Jean‐Nicolas Audinot, Tom Wirtz, Henny W. Zandbergen, Herman Albert Terryn, J.M.C. Mol

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  25. Nano-clays as Potential Pseudo-antibodies for COVID-19

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  26. In vitro cytotoxicity studies of smart pH-sensitive lamivudine-loaded CaAl-LDH magnetic nanoparticles against Mel-Rm and A-549 cancer cells

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  27. Surface-functionalized layered double hydroxide nanocontainers as bile acid sequestrants for lowering hyperlipidemia

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  28. Recent progress in layered double hydroxides as a cancer theranostic nanoplatform

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  29. New insights on the expediency of Egyptian organoclays to suppress corrosiveness of acidic-produced water in Abu-Rudeis oilfield, South Sinai, by removal of scale-forming cations and sulfate-reducing bacteria: Is there a direct link to clay lamellar ordering?

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  30. Homogeneous Incorporation of Gallium into Layered Double Hydroxide Lattice for Potential Radiodiagnostics: Proof-of-Concept

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  31. Antibacterial activity and physicochemical characterization of calcium-aluminium-ciprofloxacin-layered double hydroxide

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  32. Functional Nanomaterials and their 2D and 3D Fabrications for Drug Delivery Applications

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  33. Melanoma treatment via non-specific adhesion of cancer cells using charged nano-clays in pre-clinical studies

    Scientific Reports · 2021-02-02

    Sahel N. Abduljauwad, Habib-ur-Rehman Ahmed, Vincent T. Moy

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  34. Green clay ceramics as potential nanovehicles for drug delivery applications

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  35. 2D Nanosheets—A New Class of Therapeutic Formulations against Cancer

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  36. A review on the current progress of layered double hydroxide application in biomedical sectors

    The European Physical Journal Plus · 2022-07-11

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  37. Orally administered niclosamide-based organic/inorganic hybrid suppresses SARS-CoV-2 infection

    bioRxiv (Cold Spring Harbor Laboratory) · 2022-07-19

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  38. Release behavior and cytotoxicity of captopril-intercalated layered double hydroxide for an antihypertensive drug delivery system

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  39. A comprehensive review on methotrexate containing nanoparticles; an appropriate tool for cancer treatment

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  40. pH-Responsive Inorganic/Organic Nanohybrids System for Controlled Nicotinic Acid Drug Release

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  41. Bio-Inorganic Layered Double Hydroxide Nanohybrids in Photochemotherapy: A Mini Review

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  42. Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging

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  43. Advancements in Layered Double Hydroxide-Based Chemotherapeutic Nanosystems for Cancer Treatment

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  44. Layered double hydroxides - poloxamer 188 nanocomposites based on exfoliation reassembling for improved cellular uptake and controlled delivery of methotrexate

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  45. The Next Generation COVID‐19 Antiviral; Niclosamide‐Based Inorganic Nanohybrid System Kills SARS‐CoV‐2

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  46. Layered double hydroxides and their tailored hybrids/composites: Progressive trends for delivery of natural/synthetic-drug/cosmetic biomolecules

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  47. Toward Development of a Plate Discrete Element Method: Geometry and Kinematics

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  48. Emerging Multifunctional Carbon‐Nanomaterial‐Based Biosensors for Cancer Diagnosis

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  49. Nanoarchitectonics of CTAB-modified kanemite as carrier of methotrexate

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  50. A predictive model for calculating the electrostatic intercalation efficiency of methotrexate-loaded laponite dependent on clay concentration and pH built from binding constants

    Applied Clay Science · 2025-03-15

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