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RESEARCH PAPER · Pharmaceutics · 2014

Layered Double Hydroxide-Based Nanocarriers for Drug Delivery

Xue Jun Bi, Hui Zhang, Liguang Dou

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Layered Double Hydroxide-Based Nanocarriers for Drug DeliveryOriginalBio-Layered Double Hydroxides Nanohybrids for Theranostics Applications30Mössbauer, XRD and TEM Study on the Intercalation and the Release of Drugs in/from Layered Double Hydroxides6Synthesis and characterization of flurbiprofen axetil-loaded electrospun MgAl-LDHs/poly(lactic-co-glycolic acid) composite nanofibers13Intercalation of Benzoxaborolate Anions in Layered Double Hydroxides: Toward Hybrid Formulations for Benzoxaborole Drugs43Layered double hydroxide nanoparticles for biomedical applications: Current status and recent prospects258Intercalation of organic molecules in 2D copper (II) nitroprusside: Intermolecular interactions and magnetic properties12Structural Characterisation of Complex Layered Double Hydroxides and TGA‐GC‐MS Study on Thermal Response and Carbonate Contamination in Nitrate‐ and Organic‐Exchanged Hydrotalcites72Alternative Inorganic Systems for Controlled Release Applications3Novel Nanostructured Solid Materials for Modulating Oral Drug Delivery from Solid-State Lipid-Based Drug Delivery Systems71Preparation and evaluation of PEGylated phospholipid membrane coated layered double hydroxide nanoparticles15Size-dependent Effects of Layered Double Hydroxide Nanoparticles on Cellular Functions of Mouse Embryonic Stem Cells18Inorganic layered double hydroxides as a 4-hexyl resorcinol delivery system for topical applications10Layered double hydroxide and sulindac coiled and scrolled nanoassemblies for storage and drug release59Nanoencapsulation, Nano-guard for Pesticides: A New Window for Safe Application975Drug–clay nanohybrids as sustained delivery systems129Polymeric Nanohybrids as a New Class of Therapeutic Biotransporters23Natural curcuminoids encapsulated in layered double hydroxides: a novel antimicrobial nanohybrid31A solid state NMR study of layered double hydroxides intercalated with para-amino salicylate, a tuberculosis drug24Development of bio-hybrid material based on Salmonella Typhimurium and layered double hydroxides6A Nanoscale Interface Promoting Molecular and Functional Differentiation of Neural Cells41A Blue Photoluminescent Nano Boehmite Prepared by a Solvothermal Reaction of Aluminum Hydroxide Gel in Monoethanolamine at Low Temperature5Nanostructured hybrids for the improvement of folic acid biopharmaceutical properties11Síntesis de Hidróxidos Dobles Laminares MgAlSn y CdS-MgAl y su aplicación en reacciones fotocatalíticas de óxido-reducción0Functionalizing biochar with Mg–Al and Mg–Fe layered double hydroxides for removal of phosphate from aqueous solutions287Stacking Faults and Polytypes for Layered Double Hydroxides: What Can We Learn from Simulated and Experimental X-ray Powder Diffraction Data?39Structural characterisation of nanomaterials incorporated into bioengineered samples: An electron microscopy approach0Functionalization of Surfaces in Layered Double Hydroxides and Hydroxide Salt Nanoparticles5A comparative investigation of transgene expression and gene silencing of non-functionalized layered double hydroxides versus amino-acid functionalized hydrotalcites.0Clay–Polymer Nanocomposites for Controlled Drug Release12Effects of a novel anticorrosion engineered nanomaterial on the bivalve Ruditapes philippinarum30Nanomaterials engineering for drug delivery: a hybridization approach111Hybrid nanocomposites of layered double hydroxides: an update of their biological applications and future prospects62Efficacy and Ecotoxicity of Novel Anti-Fouling Nanomaterials in Target and Non-Target Marine Species67A comparative study of co-precipitation and sol-gel synthetic approaches to fabricate cerium-substituted Mg Al layered double hydroxides with luminescence properties84Sol-Gel Synthesis and Characterization of Non-Substituted and Europium- Substituted Layered Double Hydroxides Mg3/Al1-xEux6Instant synthesis of bespoke nanoscopic photocatalysts with enhanced surface area and photocatalytic activity for wastewater treatment33Gadolinium-based layered double hydroxide and graphene oxide nano-carriers for magnetic resonance imaging and drug delivery73The Prospects of Layered Alumino-silicates in the Synthesis of Nano-Excipients for Controlled Release Systems0Novel Nano Boehmite prepared by Solvothermal reaction of aluminum hydroxide gel in Monoethanolamine9Synthesis and Physico-Chemical Properties of Zinc Layered Hydroxide-3-4-Dichlorohenoxy Acetic Acid (ZLH34D) Nanocomposite1Polyoxometalate (POM)-Layered Double Hydroxides (LDH) Composite Materials: Design and Catalytic Applications126Nanoclays for Biomedical Applications26Nanofillers in the electrolytes of dye-sensitized solar cells – A short review74The use of Zn-Ti layered double hydroxide interlayer spacing property for low-loading drug and low-dose therapy. Synthesis, characterization and release kinetics study39Etoposide loaded layered double hydroxide nanoparticles reversing chemoresistance and eradicating human glioma stem cells in vitro and in vivo53Using of Hybrid Nanoantibiotics as Promising Antimicrobial Agent0Layered Double Hydroxide‐Based Functional Nanohybrids as Controlled Release Carriers of Pharmaceutically Active Ingredients18Influence of Chromium (III) Insertion on the Thermal Stability of Carbonated Magnesium and Aluminum Hydrotalcites Synthesized by the Hydroxide Coprecipitation Method2Graphene Oxide as a Nanocarrier for a Theranostics Delivery System of Protocatechuic Acid and Gadolinium/Gold Nanoparticles40Biocompatible nanocomposite of carboxymethyl cellulose and functionalized carbon–norfloxacin intercalated layered double hydroxides53Electrochemical Fabrication of Nanostructured Metal Oxides for the Oxygen Evolution Reaction0Highly Controlled Diffusion Drug Release from Ureasil–Poly(ethylene oxide)–Na+–Montmorillonite Hybrid Hydrogel Nanocomposites47Synthesis and application of layered double hydroxide-hosted 2-aminoterephthalate for the Knoevenagel condensation reaction6High-efficient adsorption of phosphates from water by hierarchical CuAl/biomass carbon fiber layered double hydroxide106Photodynamic treatment with anionic nanoclays containing curcumin on human triple‐negative breast cancer cells: Cellular and biochemical studies51Synthesis and catalytic activity of Mo(II) complexes of α-diimines intercalated in layered double hydroxides14Intercalations and Characterization of Zinc/Aluminium Layered Double Hydroxide-Cinnamic Acid11Layered Double Hydroxide-Decorated Hydrogel for Biomedical Applications2LDH-interlayered nanostructures for biomedical and environmental applications1Nanoclays for Biomedical Applications41Recent advances in additive‐enhanced polymer electrolyte membrane properties in fuel cell applications: An overview182Nickel(III) containing layered double hydroxides with hydrotalcite structure1Layered double hydroxides and their composites : design, synthesis and specific applications0New Approach in Ulcer Prevention and Wound Healing Treatment using Doxycycline and Amoxicillin/LDH Nanocomposites52Uptake/release of vancomycin on/from Mg–Al layered double hydroxides11Layered double hydroxide based bionanocomposites129Tuneable functionalities in layered double hydroxide catalysts for thermochemical conversion of biomass-derived glucose to fructose62Chlorogenic acid intercalated Gadolinium–Zinc/Aluminium layered double hydroxide and gold nanohybrid for MR imaging and drug delivery49Semiconductor supported by palygorskite and layered double hydroxides clays to dye discoloration in solution by a photocatalytic process32Synthesis of novel cone-shaped CaAl-LDH directly on aluminum alloy by a facile urea hydrolysis method21Engineering polyoxometalate-intercalated layered double hydroxides for catalytic applications53Amino acid–intercalated layered double hydroxide core @ ordered porous silica shell as drug carriers: Design and applications9Photocatalytic self-cleaning properties of Mo:TiO2 loaded Zn–Al layered double hydroxide synthesised at optimised pH value for the application on mineral substrates12Layered rare-earth hydroxides: a new family of anion-exchangeable layered inorganic materials57Materials for Solid-Phase Extraction of Organic Compounds72Layered double hydroxide based nanocomposites for biomedical applications7Layered Metal Hydroxides and Their Derivatives: Controllable Synthesis, Chemical Exfoliation, and Electrocatalytic Applications148Recent developments in the use of organic–inorganic nanohybrids for drug delivery51A facile synthesis of layered double hydroxide based core@shell hybrid materials23Future prospects and commercial viability of two-dimensional nanostructures for biomedical technology5New insights into two ciprofloxacin-intercalated arrangements for layered double hydroxide carrier materials19Advances in coatings on biodegradable magnesium alloys419Electrospun poly(lactic acid) nanofibers loaded with silver sulfadiazine/[Mg–Al]‐layered double hydroxide as an antimicrobial wound dressing52Curcumin Incorporation into Zn3Al Layered Double Hydroxides—Preparation, Characterization and Curcumin Release16Synthesis of novel core@shell of MgAl layered double hydroxide @ porous magnetic shell (MgAl-LDH@PMN) as carrier for ciprofloxacin drug56Advanced applications of nanotechnology in agriculture: An overview4Detoxification of hemicellulosic hydrolisate from sugarcane bagasse by adsorption on layered double hydroxides using stirred-tank and tubular reactors0Graphene-supported organic-inorganic layered double hydroxides and their environmental applications: A review81Layered double hydroxides as heterostructure LDH@Bi2WO6 oriented toward visible-light-driven applications: synthesis, characterization, and its photocatalytic properties12Effects of organo-LDH dispersion on thermal stability, crystallinity and mechanical features of PLA26Increased Cytotoxic Efficacy of Protocatechuic Acid in A549 Human Lung Cancer Delivered via Hydrophobically Modified-Chitosan Nanoparticles As an Anticancer Modality39New insights in MgAl and MgFe-LDH affinity towards carbon dioxide – role of the hydrophilic character on CO2 retention strength27Layered double hydroxides are still out in the bloom: Syntheses, applications and advantages of three-dimensional flower-like structures83Layered double hydroxides (LDHs) as functional materials for the corrosion protection of aluminum alloys: A review183Synthesis and application of magnetic@layered double hydroxide as an anti-inflammatory drugs nanocarrier63Advanced drug delivery applications of layered double hydroxide306A class of novel luminescent layered double hydroxide nanotubes15Ibuprofen Release from Hydrotalcite-like Materials Filled into Chitosan/Alginate Composites as Promising Reabsorbable Membranes6Nanotechnological Approaches for Efficient Delivery of Plant Ingredients15Synthesis of Layered Double Hydroxides Intercalated With Drugs for Controlled Release: Successful Intercalation of Ibuprofen and Failed Intercalation of Paracetamol21Immunomodulatory Layered Double Hydroxide Nanoparticles Enable Neurogenesis by Targeting Transforming Growth Factor‑β Receptor 2131Functionalized layered double hydroxide with compound to remove cationic and anionic pollutants: A review9Heparin-Tagged PLA-PEG Copolymer-Encapsulated Biochanin A-Loaded (Mg/Al) LDH Nanoparticles Recommended for Non-Thrombogenic and Anti-Proliferative Stent Coating19Advances in coatings on magnesium alloys for cardiovascular stents – A review173Sulfite‐Inserted MgAl Layered Double Hydroxides Loaded with Glucose Oxidase to Enable SO2‐Mediated Synergistic Tumor Therapy43Optimization and Pharmacokinetic Evaluation of Synergistic Fenbendazole and Rapamycin Co-Encapsulated in Methoxy Poly(Ethylene Glycol)-b-Poly(Caprolactone) Polymeric Micelles13Hydrotalcite-Embedded Magnetite Nanoparticles for Hyperthermia-Triggered Chemotherapy9Layered Double Hydroxide Nanomaterials: Biomedical Applications, Current Status and Challenges11Layered Double Hydroxide-Based Gas Sensors for VOC Detection at Room Temperature49Fabrication and characterization of a Layered Double Hydroxide based catalase biosensor and a catalytic sensor for hydrogen peroxide determination16Conventional or mechanochemically-aided intercalation of diclofenac and naproxen anions into the interlamellar space of CaFe-layered double hydroxides and their application as dermal drug delivery systems31A review of alternative polymer electrolyte membrane for fuel cell application based on sulfonated poly(ether ether ketone)117Nanotubos de hidróxidos lamelares: composição, estrutura e luminescência0Study of the chemical and phase transformations in the mechanochemical synthesis of the MgAl-layered double hydroxide21Fabrication, in vitro and ex vivo evaluation of proliposomes and liposomal derived gel for enhanced solubility and permeability of diacerein33A New Clark-Type Layered Double Hydroxides-Enzyme Biosensor for H2O2 Determination in Highly Diluted Real Matrices: Milk and Cosmetics11A Review on Nanopesticides for Plant Protection Synthesized Using the Supramolecular Chemistry of Layered Hydroxide Hosts50Synthesis and Structural Analysis of Ternary Ca–Al–Fe Layered Double Hydroxides with Different Iron Contents15Zn/Al Layered double hydroxides nanostructure as effective controlled release vehicle of nicotinic acid for topical applications21Synthesis and applications of calcium-aluminum layered double hydroxides - an overview4Layered zinc hydroxide as vehicle for drug delivery systems: a critical review21Nanolayered Double Hydroxide Inhibits the Pathogenicity of Vibrio parahaemolyticus2Layered Double Hydroxide Catalysts Preparation, Characterization and Applications for Process Development: An Environmentally Green Approach10Fabrication of superparamagnetic adsorbent based on layered double hydroxide as effective nanoadsorbent for removal of Sb (III) from water samples9Divalent metal release and antimicrobial effects of layered double hydroxides44rBMSC osteogenic differentiation enhanced by graphene quantum dots loaded with immunomodulatory layered double hydroxide nanoparticles28Synthesis and characterization of Co(II)–Co(III) LDH and Ac@Co(II)–Co(III) LDH nanohybrid and study of its application as bactericidal agents11Carboxymethyl starch encapsulated 5-FU and DOX co-loaded layered double hydroxide for evaluation of its in vitro performance as a drug delivery agent52Nanoscale layered double hydroxide modified hybrid nanomaterials for wastewater treatment: A review64Journey to the Market: The Evolution of Biodegradable Drug Delivery Systems29Environmentally Friendly Layered Double Hydroxide Conversion Layers: Formation Kinetics on Zn–Al–Mg-Coated Steel40“Smart” nanosensors for early detection of corrosion: Environmental behavior and effects on marine organisms28Visible-Light-Active Zn–Fe Layered Double Hydroxide (LDH) for the Photocatalytic Conversion of Rice Husk Extract to Value-Added Products10Direct contact, dissolution and generation of reactive oxygen species: How to optimize the antibacterial effects of layered double hydroxides34Review on chloride transport in alkali-activated materials: Role of precursors, activators and admixtures39The emergence of nanoporous materials in lung cancer therapy35Cold sintering yields first layered double hydroxides (LDH) monolithic materials14Preparation and characterization of ketoprofen and pentoxifylline agents based layered double hydroxides-chitosan nanohybride and its releasing control3Stability Trends in Mono-Metallic 3d Layered Double Hydroxides17Recent advances in Carbon Dots/2-D hybrid materials57Carbonate-free CoAl layered double hydroxides supercapacitors: Controlled precipitation via acid mediated decomplexation21Size and surface charge effect of layered double hydroxide particles upon blood cells11Comparative Study of the CO2 Methanation Activity of Hydrotalcite-Based Nickel Catalysts Generated by Using Different Reduction Protocols9Cellulose-based activated carbon/layered double hydroxide for efficient removal of Clarithromycin residues and efficient role in the treatment of stomach ulcers and acidity problems17A review on the current progress of layered double hydroxide application in biomedical sectors21Impact of Nanolayered Material and Nanohybrid Modifications on Their Potential Antibacterial Activity3Cyclodextrin-Based Arsenal for Anti-Cancer Treatments8Hidróxidos Dobles Laminares (HDL) como material adsorbente en descontaminación de aguas contaminadas por colorantes azoicos0Development of Co-Al LDH/GO composite photocatalyst for enhanced degradation of textile pollutant under visible light irradiation38Surface synthesization of magnesium alloys for improving corrosion resistance and implant applications14

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  4. Intercalation of Benzoxaborolate Anions in Layered Double Hydroxides: Toward Hybrid Formulations for Benzoxaborole Drugs

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  34. A comparative study of co-precipitation and sol-gel synthetic approaches to fabricate cerium-substituted Mg Al layered double hydroxides with luminescence properties

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  35. Sol-Gel Synthesis and Characterization of Non-Substituted and Europium- Substituted Layered Double Hydroxides Mg3/Al1-xEux

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  44. The use of Zn-Ti layered double hydroxide interlayer spacing property for low-loading drug and low-dose therapy. Synthesis, characterization and release kinetics study

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  45. Etoposide loaded layered double hydroxide nanoparticles reversing chemoresistance and eradicating human glioma stem cells in vitro and in vivo

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  46. Using of Hybrid Nanoantibiotics as Promising Antimicrobial Agent

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  47. Layered Double Hydroxide‐Based Functional Nanohybrids as Controlled Release Carriers of Pharmaceutically Active Ingredients

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