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RESEARCH PAPER · Applied Clay Science · 2012

Intracellular trafficking pathway of layered double hydroxide nanoparticles in human cells: Size-dependent cellular delivery

Hae-Eun Chung, Dae-Hwan Park, Jin‐Ho Choy, Soo‐Jin Choi

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Intracellular trafficking pathway of layered double hydroxide nanoparticles in human cells: Size-dependent cellular deliveryOriginalInorganic nanovectors for nucleic acid delivery26Multifunctional hybrid silica nanoparticles for controlled doxorubicin loading and release with thermal and pH dual response148Bioinspired Layered Nanoclays for Nutraceutical Delivery System18Isomorphous substitution of divalent metal ions in layered double hydroxides through a soft chemical hydrothermal reaction41Antimicrobial Clay-Based Materials for Wound Care40Particle size- and number-dependent delivery to cells by layered double hydroxide nanoparticles33Improvement of pharmacokinetic and antitumor activity of layered double hydroxide nanoparticles by coating with PEGylated phospholipid membrane25Physicochemical analysis methods for nanomaterials considering their toxicological evaluations9Bio-Layered Double Hydroxides Nanohybrids for Theranostics Applications30Size-tunable LDH–protein hybrids toward the optimization of drug nanocarriers19Layered double hydroxide nanoparticles for biomedical applications: Current status and recent prospects258Synthesis of methotrexatum intercalated layered double hydroxides by different methods: Biodegradation process and bioassay explore26Size-dependent Effects of Layered Double Hydroxide Nanoparticles on Cellular Functions of Mouse Embryonic Stem Cells18Effect of the protein corona on the colloidal stability and reactivity of LDH-based nanocarriers67Principles of Nanotoxicology6Biodegradable Inorganic Nanovector: Passive versus Active Tumor Targeting in siRNA Transportation140Biodegradable Inorganic Nanovector: Passive versus Active Tumor Targeting in siRNA Transportation12A novel platform designed by Au core/inorganic shell structure conjugated onto MTX/LDH for chemo-photothermal therapy21Enabling Nanohybrid Drug Discovery through the Soft Chemistry Telescope27A comparative investigation of transgene expression and gene silencing of non-functionalized layered double hydroxides versus amino-acid functionalized hydrotalcites.0Risedronate functionalized layered double hydroxides nanoparticles with bone targeting capabilities19The fabrication of layered double hydroxides based bio-materials and their application in theranostic and drug delivery1Morphology effect of nano-hydroxyapatite as a drug carrier of methotrexate172D Nanostructured Metal Hydroxides with Gene Delivery and Theranostic Functions; A Comprehensive Review58Layered Double Hydroxide Nanomaterials Encapsulating Angelica gigas Nakai Extract for Potential Anticancer Nanomedicine33Cytotoxicity and Biokinetic Evaluation of Clay Minerals7Functional Layered Double Hydroxide Nanohybrids for Biomedical Imaging472-Dimensional Nanomaterials with Imaging and Diagnostic Functions for Nanomedicine; A Review50Evaluation of intercalated layered materials as an antimicrobial and drug delivery system: a comparative study35Biocompatible Hydrotalcite Nanohybrids for Medical Functions45CoAl-layered double hydroxide nanosheet-based fluorescence assay for fast DNA detection22Size matters: Zebrafish (Danio rerio) as a model to study toxicity of nanoplastics from cells to the whole organism158Ceramic layered double hydroxide nanohybrids for therapeutic applications14Recent progress in layered double hydroxides as a cancer theranostic nanoplatform39Recent advances in LDH-based nanosystems for cancer therapy63Inorganic–inorganic nanohybrids for drug delivery, imaging and photo-therapy: recent developments and future scope94Two-dimensional biomaterials: material science, biological effect and biomedical engineering applications285Boosting the anticancer activity of doxorubicin with a layered double hydroxide nanocarrier36Emerging 2D nanomaterials for biomedical applications349Layered Double Hydroxide Nanomaterials: Biomedical Applications, Current Status and Challenges11Converging 2D Nanomaterials and 3D Bioprinting Technology: State‐of‐the‐Art, Challenges, and Potential Outlook in Biomedical Applications29Artesunate drug-loaded 2D nano-shuttle landing on RBCs infected with malaria parasites7Strategy for Cytoplasmic Delivery Using Inorganic Particles27Dual Inhibitions on Glucose/Glutamine Metabolisms for Nontoxic Pancreatic Cancer Therapy42A review on the current progress of layered double hydroxide application in biomedical sectors21Generic prediction of exocytosis rate constants by size-based surface energies of nanoparticles and cells6Surface modification of two-dimensional layered double hydroxide nanoparticles with biopolymers for biomedical applications87Biofunctional Layered Double Hydroxide Nanohybrids for Cancer Therapy17Nanoparticles in bodily tissues: predicting their equilibrium distributions8Tracking cellular uptake, intracellular trafficking and fate of nanoclay particles in human bone marrow stromal cells9State-of-the-art advancement of surface functionalized layered double hydroxides for cell-specific targeting of therapeutics26Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging59Synthesis of 20-nm-sized CoAl-LDH nanoparticles modified with folic acid for enhanced cancer cell targeting5Differential cellular uptake and trafficking of nanoplastics in two hemocyte subpopulations of mussels Perna viridis17Layered Double Hydroxide Nanostructures as Biocompatible Drug Release Agents: Synthesis, Fundamentals, Modification, and Recent Progress0The role of chorion integrity on the bioaccumulation and toxicity of selenium nanoparticles in Japanese medaka (Oryzias latipes)7Biotransport and toxic effects of micro- and nanoplastics in fish model and their potential risk to humans: A review14Biointerface Behavior of Layered Double Hydroxides: Dispersibility and Toxicity Assessment Using Experimental and Computational Models0Layered double hydroxides based nanomaterials: recent advances in drug delivery and biomedical applications7The Hidden Poison: How Microplastics and Nanoplastics Threaten the Health of Aquatic Organisms Across Ecosystems2

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  1. Inorganic nanovectors for nucleic acid delivery

    Drug Delivery and Translational Research · 2012-12-04

    Sandhya Pranatharthiharan, Mitesh D. Patel, Anisha A. D’souza, Padma V. Devarajan

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  2. Multifunctional hybrid silica nanoparticles for controlled doxorubicin loading and release with thermal and pH dual response

    Journal of Materials Chemistry B · 2012-12-13

    Xixue Hu, Xiaohong Hao, Yan Fen Wu, Jinchao Zhang, Xiaoning Zhang, Paul C. Wang, Guozhang Zou, Xing‐Jie Liang

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  3. Bioinspired Layered Nanoclays for Nutraceutical Delivery System

    ACS symposium series · 2013-01-01

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  4. Isomorphous substitution of divalent metal ions in layered double hydroxides through a soft chemical hydrothermal reaction

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    Tae-Hyun Kim, Won–Jae Lee, Jiyeong Lee, Seung‐Min Paek, Jae‐Min Oh

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  5. Antimicrobial Clay-Based Materials for Wound Care

    Future Medicinal Chemistry · 2014-04-01

    Elsie E. Gaskell, Ashley R Hamilton

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  6. Particle size- and number-dependent delivery to cells by layered double hydroxide nanoparticles

    Journal of Colloid and Interface Science · 2014-09-16

    Haiyan Dong, Harendra S. Parekh, Zhi Ping Xu

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  7. Improvement of pharmacokinetic and antitumor activity of layered double hydroxide nanoparticles by coating with PEGylated phospholipid membrane

    International Journal of Nanomedicine · 2014-10-01

    Chunshun Zhao, Mina Yan, Zhaoguo Zhang, Shengmiao Cui, Ming Lei, Ke Zeng, Yunhui Liao, Weijing Chu, Yihui Deng

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  8. Physicochemical analysis methods for nanomaterials considering their toxicological evaluations

    Molecular & Cellular Toxicology · 2014-12-01

    Kyoung‐Min Kim, Jae Ho Song, Minkyu Kim, Seung-Tae Chung, Jayoung Jeong, Jun-Young Yang, Ae-Jin Choi, Hyun‐Jin Choi, Jae‐Min Oh

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  9. Bio-Layered Double Hydroxides Nanohybrids for Theranostics Applications

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  10. Size-tunable LDH–protein hybrids toward the optimization of drug nanocarriers

    Journal of Materials Chemistry B · 2015-01-01

    Ricardo Rojas, Carla E. Giacomelli

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  11. Layered double hydroxide nanoparticles for biomedical applications: Current status and recent prospects

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  12. Synthesis of methotrexatum intercalated layered double hydroxides by different methods: Biodegradation process and bioassay explore

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    De-Ying Tian, Yu Wang, Shu-Ping Li, Xiaodong Li

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  13. Size-dependent Effects of Layered Double Hydroxide Nanoparticles on Cellular Functions of Mouse Embryonic Stem Cells

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  14. Effect of the protein corona on the colloidal stability and reactivity of LDH-based nanocarriers

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    Cecilia Vasti, Dariana Aristizábal Bedoya, Ricardo Rojas, Carla E. Giacomelli

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  15. Principles of Nanotoxicology

    Elsevier eBooks · 2016-01-01

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  16. Biodegradable Inorganic Nanovector: Passive versus Active Tumor Targeting in siRNA Transportation

    Angewandte Chemie International Edition · 2016-02-16

    Dae‐Hwan Park, Jaeyong Cho, Oh‐Joon Kwon, Chae‐Ok Yun, Jin‐Ho Choy

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  17. Biodegradable Inorganic Nanovector: Passive versus Active Tumor Targeting in siRNA Transportation

    Angewandte Chemie · 2016-02-16

    Dae‐Hwan Park, Jaeyong Cho, Oh‐Joon Kwon, Chae‐Ok Yun, Jin‐Ho Choy

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  18. A novel platform designed by Au core/inorganic shell structure conjugated onto MTX/LDH for chemo-photothermal therapy

    International Journal of Pharmaceutics · 2016-03-17

    De-Ying Tian, Weiyuan Wang, Shu-Ping Li, Xiaodong Li, Zhao-Lin Sha

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  19. Enabling Nanohybrid Drug Discovery through the Soft Chemistry Telescope

    Industrial & Engineering Chemistry Research · 2016-10-11

    Goeun Choi, Huiyan Piao, Myung Hun Kim, Jin‐Ho Choy

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  20. A comparative investigation of transgene expression and gene silencing of non-functionalized layered double hydroxides versus amino-acid functionalized hydrotalcites.

    ResearchSpace (University of KwaZulu-Natal) · 2017-01-01

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  21. Risedronate functionalized layered double hydroxides nanoparticles with bone targeting capabilities

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    Dariana Aristizábal Bedoya, Cecilia Vasti, Ricardo Rojas, Carla E. Giacomelli

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  22. The fabrication of layered double hydroxides based bio-materials and their application in theranostic and drug delivery

    Scientia Sinica Chimica · 2017-03-30

    Ruizheng Liang, Min Wei, Liuqi Peng, Xuan Mei

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  23. Morphology effect of nano-hydroxyapatite as a drug carrier of methotrexate

    Journal of Materials Science Materials in Medicine · 2017-09-13

    Haina Sun, Shanshan Liu, Xiongfeng Zeng, Xianguang Meng, Lina Zhao, Yizao Wan, Guifu Zuo

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  24. 2D Nanostructured Metal Hydroxides with Gene Delivery and Theranostic Functions; A Comprehensive Review

    The Chemical Record · 2018-02-08

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  25. Layered Double Hydroxide Nanomaterials Encapsulating Angelica gigas Nakai Extract for Potential Anticancer Nanomedicine

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  26. Cytotoxicity and Biokinetic Evaluation of Clay Minerals

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  27. Functional Layered Double Hydroxide Nanohybrids for Biomedical Imaging

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  28. 2-Dimensional Nanomaterials with Imaging and Diagnostic Functions for Nanomedicine; A Review

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  29. Evaluation of intercalated layered materials as an antimicrobial and drug delivery system: a comparative study

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  30. Biocompatible Hydrotalcite Nanohybrids for Medical Functions

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  31. CoAl-layered double hydroxide nanosheet-based fluorescence assay for fast DNA detection

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  32. Size matters: Zebrafish (Danio rerio) as a model to study toxicity of nanoplastics from cells to the whole organism

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  34. Recent progress in layered double hydroxides as a cancer theranostic nanoplatform

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  35. Recent advances in LDH-based nanosystems for cancer therapy

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  38. Boosting the anticancer activity of doxorubicin with a layered double hydroxide nanocarrier

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  42. Artesunate drug-loaded 2D nano-shuttle landing on RBCs infected with malaria parasites

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  43. Strategy for Cytoplasmic Delivery Using Inorganic Particles

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  44. Dual Inhibitions on Glucose/Glutamine Metabolisms for Nontoxic Pancreatic Cancer Therapy

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  45. A review on the current progress of layered double hydroxide application in biomedical sectors

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  46. Generic prediction of exocytosis rate constants by size-based surface energies of nanoparticles and cells

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  47. Surface modification of two-dimensional layered double hydroxide nanoparticles with biopolymers for biomedical applications

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  49. Nanoparticles in bodily tissues: predicting their equilibrium distributions

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  50. Tracking cellular uptake, intracellular trafficking and fate of nanoclay particles in human bone marrow stromal cells

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