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RESEARCH PAPER · International Journal of Pharmaceutics · 2010

Inorganic-polymer nanohybrid carrier for delivery of a poorly-soluble drug, ursodeoxycholic acid

Goeun Choi, Ji Hee Lee, Yeonji Oh, Young Bin Choy, Young Bin Choy, Myung Chul Park, Hee Chul Chang, Jin‐Ho Choy

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42 direct citing works

Inorganic-polymer nanohybrid carrier for delivery of a poorly-soluble drug, ursodeoxycholic acidOriginalThe addition of nano-sized hydroxyapatite to a sports drink to inhibit dental erosion—In vitro study using bovine enamel79Solid dispersions, Part II: new strategies in manufacturing methods for dissolution rate enhancement of poorly water-soluble drugs73Synthesis of chitosan-coated near-infrared layered double hydroxide nanoparticles for in vivo optical imaging90Drug‐Ceramic 2‐Dimensional Nanoassemblies for Drug Delivery System in Physiological Condition33Inorganic matrices: an answer to low drug solubility problem33The systems containing clays and clay minerals from modified drug release: A review205LDH in Physical, Chemical, Biochemical, and Life Sciences40Drug-inorganic-polymer nanohybrid for transdermal delivery43Polymer–inorganic supramolecular nanohybrids for red, white, green, and blue applications115A novel high-pressure precipitation tandem homogenization technology for drug nanocrystals production – a case study with ursodeoxycholic acid23A colorimetric chemosensor for F− based on Alizarin complexone and layered double hydroxide ultrafilms15Inorganic Nanovehicle Targets Tumor in an Orthotopic Breast Cancer Model68The protective effect of layered double hydroxide against damage to DNA induced by heavy metals19Protective efficacy of ursodeoxycholic acid nanoparticles in animal model of inflammatory bowel disease14Nanohybrid Based on Antibiotic Encapsulated Layered Double Hydroxide as a Drug Delivery System20Bio-Layered Double Hydroxides Nanohybrids for Theranostics Applications302D Inorganic–Antimalarial Drug–Polymer Hybrid with pH‐Responsive Solubility21Multi-laminated metal hydroxide nanocontainers for oral-specific delivery for bioavailability improvement and treatment of inflammatory paw edema in mice43Novel Nanostructured Solid Materials for Modulating Oral Drug Delivery from Solid-State Lipid-Based Drug Delivery Systems71Theranostic Bioabsorbable Bone Fixation Plate with Drug‐Layered Double Hydroxide Nanohybrids33Enabling Nanohybrid Drug Discovery through the Soft Chemistry Telescope27Precise size control of layered double hydroxide nanoparticles through reconstruction using tripodal ligands30Structural and morphological aspects of (fluoro)quinolone delivery by layered double hydroxide nanoparticles4Stabilization of antioxidant gallate in layered double hydroxide by exfoliation and reassembling reaction23Alendronate-Anionic Clay Nanohybrid for Enhanced Osteogenic Proliferation and Differentiation21Vectorized Clay Nanoparticles in Therapy and Diagnosis15Carboxymethylcellulose-coated magnesium-layered hydroxide nanocomposite for controlled release of 3-(4-methoxyphenyl)propionic acid6Layered Double Hydroxides: A Toolbox for Chemistry and Biology156Layered Double Hydroxide2Niclosamide–Clay Intercalate Coated with Nonionic Polymer for Enhanced Bioavailability toward COVID-19 Treatment41Hydrotalcite–Niclosamide Nanohybrid as Oral Formulation towards SARS-CoV-2 Viral Infections27Niclosamide encapsulated in mesoporous silica and geopolymer: A potential oral formulation for COVID-1931Artesunate drug-loaded 2D nano-shuttle landing on RBCs infected with malaria parasites7Enhancing Dissolution and Oral Bioavailability of Ursodeoxycholic Acid with a Spray-Dried pH-Modified Extended Release Formulation11pH-Responsive Inorganic/Organic Nanohybrids System for Controlled Nicotinic Acid Drug Release11Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging59Recent advances of layered double hydroxide nanohybrids for photothermal therapy2Layered Double Hydroxide Nanostructures as Biocompatible Drug Release Agents: Synthesis, Fundamentals, Modification, and Recent Progress0Multifunctional Liposome Delivery System Based on Ursodeoxycholic Acid Sodium for the Encapsulation of Silibinin and Combined Treatment of Alcoholic Liver Injury2Repurposing niclosamide for COVID-19: Synergistic strategies of nanotechnology and novel materials to enhance antiviral efficacy0Molecular insights into the encapsulation and dynamics of ursodeoxycholic acid in the γ-cyclodextrin-based MOF0

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41 direct citing papers saved.

  1. The addition of nano-sized hydroxyapatite to a sports drink to inhibit dental erosion—In vitro study using bovine enamel

    Journal of Dentistry · 2011-07-08

    Ji‐Hyun Min, Ho-Keun Kwon, Baek‐Il Kim

    Read original paper ↗ ·

  2. Solid dispersions, Part II: new strategies in manufacturing methods for dissolution rate enhancement of poorly water-soluble drugs

    Expert Opinion on Drug Delivery · 2011-09-16

    Dimitrios Ν. Bikiaris

    Read original paper ↗ ·

  3. Synthesis of chitosan-coated near-infrared layered double hydroxide nanoparticles for in vivo optical imaging

    Journal of Materials Chemistry · 2012-01-01

    Pei‐Ru Wei, Shih‐Hsun Cheng, Wei‐Neng Liao, Kun‐Che Kao, Ching‐Feng Weng, Chia‐Hung Lee

    Read original paper ↗ ·

  4. Drug‐Ceramic 2‐Dimensional Nanoassemblies for Drug Delivery System in Physiological Condition

    Journal of the American Ceramic Society · 2012-05-08

    Goeun Choi, Su Yeon Kim, Jae‐Min Oh, Jin‐Ho Choy

    Read original paper ↗ ·

  5. Inorganic matrices: an answer to low drug solubility problem

    Expert Opinion on Drug Delivery · 2012-10-12

    Luana Perioli, Cinzia Pagano

    Read original paper ↗ ·

  6. The systems containing clays and clay minerals from modified drug release: A review

    Colloids and Surfaces B Biointerfaces · 2012-11-20

    Luís Alberto de Sousa Rodrigues, Ana Figueiras, Francisco Veiga, Rivelilson Mendes de Freitas, Lívio César Cunha Nunes, Edson C. Silva-Filho, Cleide Maria da Silva Leite

    Read original paper ↗ ·

  7. LDH in Physical, Chemical, Biochemical, and Life Sciences

    Developments in clay science · 2013-01-01

    Umberto Costantino, Fabrice Leroux, Morena Nocchetti, Christine Mousty

    Read original paper ↗ ·

  8. Drug-inorganic-polymer nanohybrid for transdermal delivery

    International Journal of Pharmaceutics · 2013-01-25

    Myung Hun Kim, Dae‐Hwan Park, Jae‐Hun Yang, Young Bin Choy, Jin‐Ho Choy

    Read original paper ↗ ·

  9. Polymer–inorganic supramolecular nanohybrids for red, white, green, and blue applications

    Progress in Polymer Science · 2013-05-13

    Dae‐Hwan Park, Seong‐Ju Hwang, Jae‐Min Oh, Jae‐Hun Yang, Jin‐Ho Choy

    Read original paper ↗ ·

  10. A novel high-pressure precipitation tandem homogenization technology for drug nanocrystals production – a case study with ursodeoxycholic acid

    Pharmaceutical Development and Technology · 2013-07-22

    Yu Li, Yong Wang, Pengfei Yue, Pengyi Hu, Zhenfeng Wu, Ming Yang, Hai-Long Yuan

    Read original paper ↗ ·

  11. A colorimetric chemosensor for F− based on Alizarin complexone and layered double hydroxide ultrafilms

    Sensors and Actuators B Chemical · 2013-07-29

    Yankun Jia, Zhixiong Li, Wenying Shi

    Read original paper ↗ ·

  12. Inorganic Nanovehicle Targets Tumor in an Orthotopic Breast Cancer Model

    Scientific Reports · 2014-03-21

    Goeun Choi, Oh‐Joon Kwon, Yeonji Oh, Chae‐Ok Yun, Jin‐Ho Choy

    Read original paper ↗ ·

  13. The protective effect of layered double hydroxide against damage to DNA induced by heavy metals

    Applied Clay Science · 2014-04-03

    Pingxiao Wu, Wen Li, Yajie Zhu, Yi-ni Tang, Nengwu Zhu, Chuling Guo

    Read original paper ↗ ·

  14. Protective efficacy of ursodeoxycholic acid nanoparticles in animal model of inflammatory bowel disease

    Journal of Microencapsulation · 2014-06-25

    Amit Kumar De, Santanu Sana, Sriparna Datta, Arup Mukherjee

    Read original paper ↗ ·

  15. Nanohybrid Based on Antibiotic Encapsulated Layered Double Hydroxide as a Drug Delivery System

    Applied Biochemistry and Biotechnology · 2014-11-15

    Sher Bahadar Khan, Khalid Ahmad Alamry, Nedaa A. Alyahyawi, Abdullah Mohamed Asiri, Muhammad Nadeem Arshad, Hadi M. Marwani

    Read original paper ↗ ·

  16. Bio-Layered Double Hydroxides Nanohybrids for Theranostics Applications

    Structure and bonding · 2015-01-01

    Dae-Hwan Park, Goeun Choi, Jin‐Ho Choy

    Read original paper ↗ ·

  17. 2D Inorganic–Antimalarial Drug–Polymer Hybrid with pH‐Responsive Solubility

    Chemistry - An Asian Journal · 2015-05-12

    Ji‐Yeong Kim, Jae‐Hun Yang, Ji Hee Lee, Goeun Choi, Dae‐Hwan Park, Mi‐Rea Jo, Soo‐Jin Choi, Jin‐Ho Choy

    Read original paper ↗ ·

  18. Multi-laminated metal hydroxide nanocontainers for oral-specific delivery for bioavailability improvement and treatment of inflammatory paw edema in mice

    Journal of Colloid and Interface Science · 2015-07-20

    Ranjith Kumar Kankala, Yaswanth Kuthati, Huei-Wun Sie, Hung-Yuan Shih, Sheng‐I Lue, Shravankumar Kankala, Chien‐Chung Jeng, Jin‐Pei Deng, Ching‐Feng Weng, Chen‐Lun Liu, Chia‐Hung Lee

    Read original paper ↗ ·

  19. Novel Nanostructured Solid Materials for Modulating Oral Drug Delivery from Solid-State Lipid-Based Drug Delivery Systems

    The AAPS Journal · 2015-09-09

    Tahnee J. Dening, Shasha Rao, Nicky Thomas, Clive A. Prestidge

    Read original paper ↗ ·

  20. Theranostic Bioabsorbable Bone Fixation Plate with Drug‐Layered Double Hydroxide Nanohybrids

    Advanced Healthcare Materials · 2016-10-10

    Myung Hun Kim, Woojune Hur, Goeun Choi, Hye Sook Min, Tae Hyun Choi, Young Bin Choy, Jin‐Ho Choy

    Read original paper ↗ ·

  21. Enabling Nanohybrid Drug Discovery through the Soft Chemistry Telescope

    Industrial & Engineering Chemistry Research · 2016-10-11

    Goeun Choi, Huiyan Piao, Myung Hun Kim, Jin‐Ho Choy

    Read original paper ↗ ·

  22. Precise size control of layered double hydroxide nanoparticles through reconstruction using tripodal ligands

    Dalton Transactions · 2018-01-01

    Yoshiyuki Kuroda, Yuya Oka, Tadao YASUDA, Tatsuyuki Koichi, Keisuke Muramatsu, Hiroaki Wada, Atsushi Shimojima, Kazuyuki Kuroda

    Read original paper ↗ ·

  23. Structural and morphological aspects of (fluoro)quinolone delivery by layered double hydroxide nanoparticles

    New Journal of Chemistry · 2018-01-01

    Yadira Estefanía Salguero, Mónica Cristina García, Giuliana Mosconi, Ricardo Rojas

    Read original paper ↗ ·

  24. Stabilization of antioxidant gallate in layered double hydroxide by exfoliation and reassembling reaction

    Solid State Sciences · 2018-04-03

    Kanakappan M. Ansy, Ji Hee Lee, Huiyan Piao, Goeun Choi, Jin‐Ho Choy

    Read original paper ↗ ·

  25. Alendronate-Anionic Clay Nanohybrid for Enhanced Osteogenic Proliferation and Differentiation

    Journal of Korean Medical Science · 2019-01-01

    Huiyan Piao, Myung Hun Kim, Meiling Cui, Goeun Choi, Jin‐Ho Choy

    Read original paper ↗ ·

  26. Vectorized Clay Nanoparticles in Therapy and Diagnosis

    Clays and Clay Minerals · 2019-02-15

    Goeun Choi, Huiyan Piao, Sairan Eom, Jin‐Ho Choy

    Read original paper ↗ ·

  27. Carboxymethylcellulose-coated magnesium-layered hydroxide nanocomposite for controlled release of 3-(4-methoxyphenyl)propionic acid

    Arabian Journal of Chemistry · 2019-04-19

    Norhayati Hashim, Nor Saleha Misuan, Illyas Md Isa, Suriani Abu Bakar, Suzaliza Mustafar, Mazidah Mamat, Mohd Zobir Hussein, Sharifah Norain Mohd Sharif

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  28. Layered Double Hydroxides: A Toolbox for Chemistry and Biology

    Crystals · 2019-07-15

    Giuseppe Arrabito, Aurelio Bonasera, Giuseppe Prestopino, Andrea Orsini, A. Mattoccia, Eugenio Martinelli, Bruno Pignataro, P. G. Medaglia

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  29. Layered Double Hydroxide

    Unknown journal · 2020-10-23

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  30. Niclosamide–Clay Intercalate Coated with Nonionic Polymer for Enhanced Bioavailability toward COVID-19 Treatment

    Polymers · 2021-03-26

    Seungjin Yu, Huiyan Piao, N. Sanoj Rejinold, Geun‐woo Jin, Goeun Choi, Jin‐Ho Choy

    Read original paper ↗ ·

  31. Hydrotalcite–Niclosamide Nanohybrid as Oral Formulation towards SARS-CoV-2 Viral Infections

    Pharmaceuticals · 2021-05-19

    Goeun Choi, Huiyan Piao, N. Sanoj Rejinold, Seungjin Yu, Ki-yeok Kim, Geun‐woo Jin, Jin‐Ho Choy

    Read original paper ↗ ·

  32. Niclosamide encapsulated in mesoporous silica and geopolymer: A potential oral formulation for COVID-19

    Microporous and Mesoporous Materials · 2021-08-28

    Huiyan Piao, N. Sanoj Rejinold, Goeun Choi, Yi‐Rong Pei, Geun‐woo Jin, Jin‐Ho Choy

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  33. Artesunate drug-loaded 2D nano-shuttle landing on RBCs infected with malaria parasites

    Biomaterials Science · 2022-01-01

    Ji‐Yeong Kim, Hyun‐Il Shin, Sang-Eun Lee, Huiyan Piao, N. Sanoj Rejinold, Goeun Choi, Jin‐Ho Choy

    Read original paper ↗ ·

  34. Enhancing Dissolution and Oral Bioavailability of Ursodeoxycholic Acid with a Spray-Dried pH-Modified Extended Release Formulation

    Pharmaceutics · 2022-05-11

    Jaehyeok Lee, Chul Haeng Lee, Jong-Geon Lee, So Yeon Jeon, Min‐Koo Choi, Im‐Sook Song

    Read original paper ↗ ·

  35. pH-Responsive Inorganic/Organic Nanohybrids System for Controlled Nicotinic Acid Drug Release

    Molecules · 2022-09-29

    Seungjin Yu, Huiyan Piao, N. Sanoj Rejinold, Hanna Lee, Goeun Choi, Jin‐Ho Choy

    Read original paper ↗ ·

  36. Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging

    Nanomaterials · 2023-03-19

    Seungjin Yu, Goeun Choi, Jin‐Ho Choy

    Read original paper ↗ ·

  37. Recent advances of layered double hydroxide nanohybrids for photothermal therapy

    Medical Lasers · 2023-03-30

    Si Eun Park, Goeun Choi

    Read original paper ↗ ·

  38. Layered Double Hydroxide Nanostructures as Biocompatible Drug Release Agents: Synthesis, Fundamentals, Modification, and Recent Progress

    Springer eBooks · 2024-11-15

    Augusto Rodríguez, Lenys Fernández, Patricio J. Espinoza-Montero

    Read original paper ↗ ·

  39. Multifunctional Liposome Delivery System Based on Ursodeoxycholic Acid Sodium for the Encapsulation of Silibinin and Combined Treatment of Alcoholic Liver Injury

    Molecular Pharmaceutics · 2025-02-11

    Yulu Wang, Minghao Yuan, Sihui Li, Jiamei Tang, Yan Wan, Xue Liang, Yiping Guo, Li Guo

    Read original paper ↗ ·

  40. Repurposing niclosamide for COVID-19: Synergistic strategies of nanotechnology and novel materials to enhance antiviral efficacy

    Microbial Pathogenesis · 2025-11-08

    Haichuan Rong, Junyi Ren, Qifeng Wu, Haijun Zhu, Chenshuang Dong, Guiling Wang

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  41. Molecular insights into the encapsulation and dynamics of ursodeoxycholic acid in the γ-cyclodextrin-based MOF

    Journal of Molecular Liquids · 2026-08-10

    Farzane Pazoki, Fatemeh Rafiee, Mina Ghiasi

    Read original paper ↗ ·
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